Human Umbilical Cord Matrix Mesenchymal Stem Cells Suppress the Growth of Breast Cancer by Expression of Tumor Suppressor Genes

Naomi Ohta; Susumu Ishiguro; Atsushi Kawabata; Deepthi Uppalapati; Marla Pyle; Deryl Troyer; Supriyo De; Yongqing Zhang; Kevin G. Becker; Masaaki Tamura

doi:10.1371/journal.pone.0123756

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Peer-reviewed

Research Article

Human Umbilical Cord Matrix Mesenchymal Stem Cells Suppress the Growth of Breast Cancer by Expression of Tumor Suppressor Genes

Naomi Ohta,

Affiliation Department of Anatomy and Physiology, College of Veterinary Medicine, Kansas State University, Manhattan, 66506, United States of America
⨯
Susumu Ishiguro,

Affiliation Department of Anatomy and Physiology, College of Veterinary Medicine, Kansas State University, Manhattan, 66506, United States of America
⨯
Atsushi Kawabata,

Affiliation Department of Anatomy and Physiology, College of Veterinary Medicine, Kansas State University, Manhattan, 66506, United States of America
⨯
Deepthi Uppalapati,

Affiliation Department of Anatomy and Physiology, College of Veterinary Medicine, Kansas State University, Manhattan, 66506, United States of America
⨯
Marla Pyle,

Affiliation Department of Anatomy and Physiology, College of Veterinary Medicine, Kansas State University, Manhattan, 66506, United States of America
⨯
Deryl Troyer,

Affiliation Department of Anatomy and Physiology, College of Veterinary Medicine, Kansas State University, Manhattan, 66506, United States of America
⨯
Supriyo De,

Affiliation Gene Expression and Genomics Unit, NIH Biomedical Research Center, National Institute on Aging, NIH, Baltimore, MD, 21224, United States of America
⨯
Yongqing Zhang,

Affiliation Gene Expression and Genomics Unit, NIH Biomedical Research Center, National Institute on Aging, NIH, Baltimore, MD, 21224, United States of America
⨯
Kevin G. Becker,

Affiliation Gene Expression and Genomics Unit, NIH Biomedical Research Center, National Institute on Aging, NIH, Baltimore, MD, 21224, United States of America
⨯
Masaaki Tamura

* E-mail: mtamura@vet.ksu.edu

Affiliation Department of Anatomy and Physiology, College of Veterinary Medicine, Kansas State University, Manhattan, 66506, United States of America
⨯

Human Umbilical Cord Matrix Mesenchymal Stem Cells Suppress the Growth of Breast Cancer by Expression of Tumor Suppressor Genes

Naomi Ohta,
Susumu Ishiguro,
Atsushi Kawabata,
Deepthi Uppalapati,
Marla Pyle,
Deryl Troyer,
Supriyo De,
Yongqing Zhang,
Kevin G. Becker,
Masaaki Tamura

Published: May 5, 2015
https://doi.org/10.1371/journal.pone.0123756

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Breast cancer
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Lung and intrathoracic tumors
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Tumor suppressor genes
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Gene expression
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