Immunization with a Live Attenuated H7N9 Influenza Vaccine Protects Mice against Lethal Challenge

Xiaolan Yang; Jianyu Zhao; Cheng Wang; Yueqiang Duan; Zhongpeng Zhao; Rui Chen; Liangyan Zhang; Li Xing; Chengcai Lai; Shaogeng Zhang; Xiliang Wang; Penghui Yang

doi:10.1371/journal.pone.0123659

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Open Access

Peer-reviewed

Research Article

Immunization with a Live Attenuated H7N9 Influenza Vaccine Protects Mice against Lethal Challenge

Xiaolan Yang ,

Contributed equally to this work with: Xiaolan Yang, Jianyu Zhao, Cheng Wang

Affiliation Beijing Institute of Microbiology and Epidemiology, State Key Laboratory of Pathogen and Biosecurity, Beijing, China
⨯
Jianyu Zhao ,

Contributed equally to this work with: Xiaolan Yang, Jianyu Zhao, Cheng Wang

Affiliation China Astronaut Research and Training Center, Beijing, China
⨯
Cheng Wang ,

Contributed equally to this work with: Xiaolan Yang, Jianyu Zhao, Cheng Wang

Affiliation Beijing 307 Hospital Affiliated to Academy of Medical Sciences, Beijing, China
⨯
Yueqiang Duan,

Affiliation Beijing Institute of Microbiology and Epidemiology, State Key Laboratory of Pathogen and Biosecurity, Beijing, China
⨯
Zhongpeng Zhao,

Affiliation Beijing Institute of Microbiology and Epidemiology, State Key Laboratory of Pathogen and Biosecurity, Beijing, China
⨯
Rui Chen,

Affiliation Beijing Institute of Microbiology and Epidemiology, State Key Laboratory of Pathogen and Biosecurity, Beijing, China
⨯
Liangyan Zhang,

Affiliation Beijing Institute of Microbiology and Epidemiology, State Key Laboratory of Pathogen and Biosecurity, Beijing, China
⨯
Li Xing,

Affiliation Beijing Institute of Microbiology and Epidemiology, State Key Laboratory of Pathogen and Biosecurity, Beijing, China
⨯
Chengcai Lai,

Affiliation Beijing Institute of Microbiology and Epidemiology, State Key Laboratory of Pathogen and Biosecurity, Beijing, China
⨯
Shaogeng Zhang,

Affiliation Beijing 302 Hospital, Beijing, China
⨯
Xiliang Wang ,

* E-mail: xiliangw@126.com (XW); ypenghuiamms@hotmail.com (PY)

Affiliation Beijing Institute of Microbiology and Epidemiology, State Key Laboratory of Pathogen and Biosecurity, Beijing, China
⨯
Penghui Yang

* E-mail: xiliangw@126.com (XW); ypenghuiamms@hotmail.com (PY)

Affiliations Beijing Institute of Microbiology and Epidemiology, State Key Laboratory of Pathogen and Biosecurity, Beijing, China, Beijing 302 Hospital, Beijing, China
⨯

Immunization with a Live Attenuated H7N9 Influenza Vaccine Protects Mice against Lethal Challenge

Xiaolan Yang,
Jianyu Zhao,
Cheng Wang,
Yueqiang Duan,
Zhongpeng Zhao,
Rui Chen,
Liangyan Zhang,
Li Xing,
Chengcai Lai,
Shaogeng Zhang

Published: April 17, 2015
https://doi.org/10.1371/journal.pone.0123659

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