Identification of Novel Adipokines in the Joint. Differential Expression in Healthy and Osteoarthritis Tissues

Javier Conde; Morena Scotece; Vanessa Abella; Rodolfo Gómez; Verónica López; Rosa Villar; Miguel Hermida; Jesús Pino; Juan Jesús Gómez-Reino; Oreste Gualillo

doi:10.1371/journal.pone.0123601

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Open Access

Peer-reviewed

Research Article

Identification of Novel Adipokines in the Joint. Differential Expression in Healthy and Osteoarthritis Tissues

Javier Conde,

Affiliation SERGAS (Servizo Galego de Saude) and IDIS (Instituto de Investigación Sanitaria de Santiago), the NEIRID Lab (Neuroendocrine Interactions in Rheumatology and Inflammatory Diseases), Research Laboratory 9, Santiago University Clinical Hospital, Santiago de Compostela, Spain
⨯
Morena Scotece,

Affiliation SERGAS (Servizo Galego de Saude) and IDIS (Instituto de Investigación Sanitaria de Santiago), the NEIRID Lab (Neuroendocrine Interactions in Rheumatology and Inflammatory Diseases), Research Laboratory 9, Santiago University Clinical Hospital, Santiago de Compostela, Spain
⨯
Vanessa Abella,

Affiliations SERGAS (Servizo Galego de Saude) and IDIS (Instituto de Investigación Sanitaria de Santiago), the NEIRID Lab (Neuroendocrine Interactions in Rheumatology and Inflammatory Diseases), Research Laboratory 9, Santiago University Clinical Hospital, Santiago de Compostela, Spain, Department of Molecular and Cellular Biology, University of Coruña (UDC), A Coruña, Spain
⨯
Rodolfo Gómez,

Affiliation SERGAS (Servizo Galego de Saude) and IDIS (Instituto de Investigación Sanitaria de Santiago), the NEIRID Lab (Neuroendocrine Interactions in Rheumatology and Inflammatory Diseases), Research Laboratory 9, Santiago University Clinical Hospital, Santiago de Compostela, Spain
⨯
Verónica López,

Affiliation SERGAS (Servizo Galego de Saude) and IDIS (Instituto de Investigación Sanitaria de Santiago), the NEIRID Lab (Neuroendocrine Interactions in Rheumatology and Inflammatory Diseases), Research Laboratory 9, Santiago University Clinical Hospital, Santiago de Compostela, Spain
⨯
Rosa Villar,

Affiliation SERGAS (Servizo Galego de Saude) and IDIS (Instituto de Investigación Sanitaria de Santiago), the NEIRID Lab (Neuroendocrine Interactions in Rheumatology and Inflammatory Diseases), Research Laboratory 9, Santiago University Clinical Hospital, Santiago de Compostela, Spain
⨯
Miguel Hermida,

Affiliation SERGAS (Servizo Galego de Saude), Division of Orthopaedics Surgery and Traumatology, Santiago University Clinical Hospital, Santiago de Compostela, Spain
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Jesús Pino,

Affiliation SERGAS (Servizo Galego de Saude), Division of Orthopaedics Surgery and Traumatology, Santiago University Clinical Hospital, Santiago de Compostela, Spain
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Juan Jesús Gómez-Reino,

Affiliation University of Santiago de Compostela, Department of Medicine and SERGAS (Servizo Galego de Saude) and IDIS (Instituto de Investigación Sanitaria de Santiago), Division of Rheumatology, Santiago University Clinical Hospital, Santiago de Compostela, Spain
⨯
Oreste Gualillo

* E-mail: oreste.gualillo@sergas.es

Affiliation SERGAS (Servizo Galego de Saude) and IDIS (Instituto de Investigación Sanitaria de Santiago), the NEIRID Lab (Neuroendocrine Interactions in Rheumatology and Inflammatory Diseases), Research Laboratory 9, Santiago University Clinical Hospital, Santiago de Compostela, Spain
⨯

Identification of Novel Adipokines in the Joint. Differential Expression in Healthy and Osteoarthritis Tissues

Javier Conde,
Morena Scotece,
Vanessa Abella,
Rodolfo Gómez,
Verónica López,
Rosa Villar,
Miguel Hermida,
Jesús Pino,
Juan Jesús Gómez-Reino,
Oreste Gualillo

Published: April 8, 2015
https://doi.org/10.1371/journal.pone.0123601

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Osteoarthritis
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Adipokines
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Chondrocytes
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Skeletal joints
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Adipose tissue
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Extracellular matrix
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Messenger RNA
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