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Open Access
Peer-reviewed
Research Article
Impact of Smoking and Brain Metastasis on Outcomes of Advanced EGFR Mutation Lung Adenocarcinoma Patients Treated with First Line Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors
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Amit Jain,
Affiliation Division of Medical Oncology, National Cancer Centre Singapore, Singapore, Singapore
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Cindy Lim,
Affiliation Clinical Trials & Epidemiological Sciences, National Cancer Centre Singapore, Singapore, Singapore
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Eugene MingJin Gan,
Affiliation Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore
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David Zhihao Ng,
Affiliation Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore
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Quan Sing Ng,
Affiliation Division of Medical Oncology, National Cancer Centre Singapore, Singapore, Singapore
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Mei Kim Ang,
Affiliation Division of Medical Oncology, National Cancer Centre Singapore, Singapore, Singapore
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Angela Takano,
Affiliation Department of Pathology, Academia, Level 7, Singapore General Hospital, Singapore, Singapore
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Kian Sing Chan,
Affiliation Department of Pathology, Academia, Level 7, Singapore General Hospital, Singapore, Singapore
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Wu Meng Tan,
Affiliation Division of Medical Oncology, National Cancer Centre Singapore, Singapore, Singapore
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Ravindran Kanesvaran,
Affiliation Division of Medical Oncology, National Cancer Centre Singapore, Singapore, Singapore
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Chee Keong Toh,
Affiliation Division of Medical Oncology, National Cancer Centre Singapore, Singapore, Singapore
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Chian Min Loo,
Affiliation Respiratory and Critical Care Medicine, Singapore General Hospital, Singapore, Singapore
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Anne Ann Ling Hsu,
Affiliation Respiratory and Critical Care Medicine, Singapore General Hospital, Singapore, Singapore
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Anantham Devanand,
Affiliation Respiratory and Critical Care Medicine, Singapore General Hospital, Singapore, Singapore
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Chong Hee Lim,
Affiliation Department of Cardiothoracic Surgery, National Heart Centre Singapore, Singapore, Singapore
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Heng Nung Koong,
Affiliation Division of Surgical Oncology, National Cancer Centre Singapore, Singapore, Singapore
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Tina Koh,
Affiliation Division of Surgical Oncology, National Cancer Centre Singapore, Singapore, Singapore
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Kam Weng Fong,
Affiliation Division of Radiation Oncology, National Cancer Centre Singapore, Singapore, Singapore
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Swee Peng Yap,
Affiliation Division of Radiation Oncology, National Cancer Centre Singapore, Singapore, Singapore
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Su Woon Kim,
Affiliation Division of Radiation Oncology, National Cancer Centre Singapore, Singapore, Singapore
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Balram Chowbay,
Affiliation Clinical Pharmacology Laboratory, Division of Medical Sciences, National Cancer Centre Singapore, Singapore, Singapore
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Lynette Oon,
Affiliation Department of Pathology, Academia, Level 7, Singapore General Hospital, Singapore, Singapore
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Kiat Hon Lim,
Affiliation Department of Pathology, Academia, Level 7, Singapore General Hospital, Singapore, Singapore
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Wan Teck Lim,
Affiliation Division of Medical Oncology, National Cancer Centre Singapore, Singapore, Singapore
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Eng Huat Tan,
Affiliation Division of Medical Oncology, National Cancer Centre Singapore, Singapore, Singapore
⨯ - [ ... ],
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Daniel Shao Weng Tan
* E-mail: daniel.tan.s.w@nccs.com.sg
Affiliations Division of Medical Oncology, National Cancer Centre Singapore, Singapore, Singapore, Cancer Therapeutics Research Laboratory, Division of Medical Sciences, National Cancer Centre Singapore, Singapore, Singapore, Cancer Stem Cell Biology, Genome Institute of Singapore, Singapore, Singapore
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Impact of Smoking and Brain Metastasis on Outcomes of Advanced EGFR Mutation Lung Adenocarcinoma Patients Treated with First Line Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors
- Amit Jain,
- Cindy Lim,
- Eugene MingJin Gan,
- David Zhihao Ng,
- Quan Sing Ng,
- Mei Kim Ang,
- Angela Takano,
- Kian Sing Chan,
- Wu Meng Tan,
- Ravindran Kanesvaran
- Published: May 8, 2015
- https://doi.org/10.1371/journal.pone.0123587