Pharmacokinetics of Repeated Sodium Salicylate Administration to Laying Hens: Evidence for Time Dependent Increase in Drug Elimination from Plasma and Eggs

Błażej Poźniak; Tomasz Grabowski; Karolina Motykiewicz-Pers; Kamila Bobrek; Lech Rak; Katarzyna Bobusia; Andrzej Gaweł; Marcin Świtała

doi:10.1371/journal.pone.0123526

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Peer-reviewed

Research Article

Pharmacokinetics of Repeated Sodium Salicylate Administration to Laying Hens: Evidence for Time Dependent Increase in Drug Elimination from Plasma and Eggs

Błażej Poźniak ,

* E-mail: blazej.pozniak@up.wroc.pl

Affiliation Department of Biochemistry, Pharmacology and Toxicology, Faculty of Veterinary Medicine, Wrocław University of Environmental and Life Sciences, Wrocław, Poland
⨯
Tomasz Grabowski,

Affiliation Polpharma Biologics, Gdańsk, Poland
⨯
Karolina Motykiewicz-Pers,

Affiliation Department of Biochemistry, Pharmacology and Toxicology, Faculty of Veterinary Medicine, Wrocław University of Environmental and Life Sciences, Wrocław, Poland
⨯
Kamila Bobrek,

Affiliation Department of Epizootiology and Clinic of Birds and Exotic Animals, Faculty of Veterinary Medicine, Wrocław University of Environmental and Life Sciences, Wrocław, Poland
⨯
Lech Rak,

Affiliation Department of Food Hygiene and Consumer Health Protection, Faculty of Veterinary Medicine, Wrocław University of Environmental and Life Sciences, Wrocław, Poland
⨯
Katarzyna Bobusia,

Affiliation Department of Epizootiology and Clinic of Birds and Exotic Animals, Faculty of Veterinary Medicine, Wrocław University of Environmental and Life Sciences, Wrocław, Poland
⨯
Andrzej Gaweł,

Affiliation Department of Epizootiology and Clinic of Birds and Exotic Animals, Faculty of Veterinary Medicine, Wrocław University of Environmental and Life Sciences, Wrocław, Poland
⨯
Marcin Świtała

Affiliation Department of Biochemistry, Pharmacology and Toxicology, Faculty of Veterinary Medicine, Wrocław University of Environmental and Life Sciences, Wrocław, Poland
⨯

Pharmacokinetics of Repeated Sodium Salicylate Administration to Laying Hens: Evidence for Time Dependent Increase in Drug Elimination from Plasma and Eggs

Błażej Poźniak,
Tomasz Grabowski,
Karolina Motykiewicz-Pers,
Kamila Bobrek,
Lech Rak,
Katarzyna Bobusia,
Andrzej Gaweł,
Marcin Świtała

Published: April 20, 2015
https://doi.org/10.1371/journal.pone.0123526

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