Effect of miR-20b on Apoptosis, Differentiation, the BMP Signaling Pathway and Mitochondrial Function in the P19 Cell Model of Cardiac Differentiation In Vitro

Shasha Zhu; Xiaoshan Hu; Zhangbin Yu; Yuzhu Peng; Jingai Zhu; Xuehua Liu; Mengmeng Li; Shuping Han; Chun Zhu

doi:10.1371/journal.pone.0123519

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Open Access

Peer-reviewed

Research Article

Effect of miR-20b on Apoptosis, Differentiation, the BMP Signaling Pathway and Mitochondrial Function in the P19 Cell Model of Cardiac Differentiation In Vitro

Shasha Zhu,

Affiliation Department of Cardiology, The First Affiliated Hospital of Soochow University, Suzhou 215006, China
⨯
Xiaoshan Hu,

Affiliation State key Laboratory of Reproductive Medicine, Department of Pediatrics, Nanjing Maternity and Child Health Care Hospital Affiliated to Nanjing Medical University, Nanjing 210004, China
⨯
Zhangbin Yu,

Affiliation State key Laboratory of Reproductive Medicine, Department of Pediatrics, Nanjing Maternity and Child Health Care Hospital Affiliated to Nanjing Medical University, Nanjing 210004, China
⨯
Yuzhu Peng,

Affiliation State key Laboratory of Reproductive Medicine, Department of Pediatrics, Nanjing Maternity and Child Health Care Hospital Affiliated to Nanjing Medical University, Nanjing 210004, China
⨯
Jingai Zhu,

Affiliation State key Laboratory of Reproductive Medicine, Department of Pediatrics, Nanjing Maternity and Child Health Care Hospital Affiliated to Nanjing Medical University, Nanjing 210004, China
⨯
Xuehua Liu,

Affiliation State key Laboratory of Reproductive Medicine, Department of Pediatrics, Nanjing Maternity and Child Health Care Hospital Affiliated to Nanjing Medical University, Nanjing 210004, China
⨯
Mengmeng Li,

Affiliation State key Laboratory of Reproductive Medicine, Department of Pediatrics, Nanjing Maternity and Child Health Care Hospital Affiliated to Nanjing Medical University, Nanjing 210004, China
⨯
Shuping Han ,

* E-mail: shupinghan@126.com (SPH); zhifangxibao@163.com (CZ)

Affiliation State key Laboratory of Reproductive Medicine, Department of Pediatrics, Nanjing Maternity and Child Health Care Hospital Affiliated to Nanjing Medical University, Nanjing 210004, China
⨯
Chun Zhu

* E-mail: shupinghan@126.com (SPH); zhifangxibao@163.com (CZ)

Affiliation State key Laboratory of Reproductive Medicine, Department of Pediatrics, Nanjing Maternity and Child Health Care Hospital Affiliated to Nanjing Medical University, Nanjing 210004, China
⨯

Effect of miR-20b on Apoptosis, Differentiation, the BMP Signaling Pathway and Mitochondrial Function in the P19 Cell Model of Cardiac Differentiation In Vitro

Shasha Zhu,
Xiaoshan Hu,
Zhangbin Yu,
Yuzhu Peng,
Jingai Zhu,
Xuehua Liu,
Mengmeng Li,
Shuping Han,
Chun Zhu

Published: April 21, 2015
https://doi.org/10.1371/journal.pone.0123519

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Cell differentiation
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Mitochondria
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Apoptosis
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BMP signaling
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MicroRNAs
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Cardiomyocytes
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Polymerase chain reaction
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