Berberine Inhibits Invasion and Metastasis of Colorectal Cancer Cells via COX-2/PGE2 Mediated JAK2/STAT3 Signaling Pathway

Open Access

Peer-reviewed

Research Article

Berberine Inhibits Invasion and Metastasis of Colorectal Cancer Cells via COX-2/PGE₂ Mediated JAK2/STAT3 Signaling Pathway

Xuan Liu ,

Contributed equally to this work with: Xuan Liu, Qing Ji

Affiliation Department of Medical Oncology, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China
⨯
Qing Ji ,

Contributed equally to this work with: Xuan Liu, Qing Ji

Affiliation Department of Medical Oncology, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China
⨯
Naijing Ye,

Affiliation Department of Medical Oncology, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China
⨯
Hua Sui,

Affiliation Department of Medical Oncology, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China
⨯
Lihong Zhou,

Affiliation Department of Medical Oncology, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China
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Huirong Zhu,

Affiliation Department of Medical Oncology, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China
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Zhongze Fan,

Affiliation Interventional Cancer Institute, Shanghai University of Traditional Chinese Medicine, Shanghai, China
⨯
Jianfeng Cai,

Affiliation Department of Chemistry, University of South Florida, Tampa, Florida, United States of America
⨯
Qi Li

* E-mail: Lzwf@hotmail.com

Affiliation Department of Medical Oncology, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China
⨯

Cancer treatment
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Colorectal cancer
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Metastasis
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Mouse models
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Lung and intrathoracic tumors
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Cancers and neoplasms
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Signal inhibition
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STAT signaling
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