Dexamethasone as Adjuvant to Bupivacaine Prolongs the Duration of Thermal Antinociception and Prevents Bupivacaine-Induced Rebound Hyperalgesia via Regional Mechanism in a Mouse Sciatic Nerve Block Model

Open Access

Peer-reviewed

Research Article

Ke An,

Affiliations Department of Anesthesiology & Critical Care, Perelman School of Medicine, the University of Pennsylvania, Philadelphia, Pennsylvania, United States of America, Department of Anesthesiology, The first affiliated hospital of Sun Yat-Sen University, Guangzhou, P.R. China
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Nabil M. Elkassabany,

Affiliation Department of Anesthesiology & Critical Care, Perelman School of Medicine, the University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
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Jiabin Liu

* E-mail: Jiabin.Liu@uphs.upenn.edu

Affiliation Department of Anesthesiology & Critical Care, Perelman School of Medicine, the University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
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Sciatic nerves
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Nerve block
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Schwann cells
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Perineural block
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Hyperalgesia
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Axons
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Analgesia
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Hematoxylin staining
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