17ß-Estradiol Regulates mTORC2 Sensitivity to Rapamycin in Adaptive Cardiac Remodeling

Angelika Kusch; Maria Schmidt; Dennis Gürgen; Daniel Postpieszala; Rusan Catar; Björn Hegner; Merci M. Davidson; Shokoufeh Mahmoodzadeh; Duska Dragun

doi:10.1371/journal.pone.0123385

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Open Access

Peer-reviewed

Research Article

17ß-Estradiol Regulates mTORC2 Sensitivity to Rapamycin in Adaptive Cardiac Remodeling

Angelika Kusch ,

* E-mail: angelika.kusch@charite.de

Affiliations Department of Nephrology and Intensive Care Medicine, Charité—Campus Virchow Klinikum, Universitätsmedizin Berlin, Berlin, Germany, Center for Cardiovascular Research, Charité, Universitätsmedizin Berlin, Berlin, Germany
⨯
Maria Schmidt,

Affiliation Department of Nephrology and Intensive Care Medicine, Charité—Campus Virchow Klinikum, Universitätsmedizin Berlin, Berlin, Germany
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Dennis Gürgen,

Affiliations Department of Nephrology and Intensive Care Medicine, Charité—Campus Virchow Klinikum, Universitätsmedizin Berlin, Berlin, Germany, Center for Cardiovascular Research, Charité, Universitätsmedizin Berlin, Berlin, Germany
⨯
Daniel Postpieszala,

Affiliation Department of Nephrology and Intensive Care Medicine, Charité—Campus Virchow Klinikum, Universitätsmedizin Berlin, Berlin, Germany
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Rusan Catar,

Affiliations Department of Nephrology and Intensive Care Medicine, Charité—Campus Virchow Klinikum, Universitätsmedizin Berlin, Berlin, Germany, Center for Cardiovascular Research, Charité, Universitätsmedizin Berlin, Berlin, Germany
⨯
Björn Hegner,

Affiliations Department of Nephrology and Intensive Care Medicine, Charité—Campus Virchow Klinikum, Universitätsmedizin Berlin, Berlin, Germany, Center for Cardiovascular Research, Charité, Universitätsmedizin Berlin, Berlin, Germany
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Merci M. Davidson,

Affiliation Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, New York, United States of America
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Shokoufeh Mahmoodzadeh,

Affiliations Center for Cardiovascular Research, Charité, Universitätsmedizin Berlin, Berlin, Germany, Max Delbrück Center for Molecular Medicine, Berlin, Germany
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Duska Dragun

Affiliations Department of Nephrology and Intensive Care Medicine, Charité—Campus Virchow Klinikum, Universitätsmedizin Berlin, Berlin, Germany, Center for Cardiovascular Research, Charité, Universitätsmedizin Berlin, Berlin, Germany
⨯

17ß-Estradiol Regulates mTORC2 Sensitivity to Rapamycin in Adaptive Cardiac Remodeling

Angelika Kusch,
Maria Schmidt,
Dennis Gürgen,
Daniel Postpieszala,
Rusan Catar,
Björn Hegner,
Merci M. Davidson,
Shokoufeh Mahmoodzadeh,
Duska Dragun

Published: April 16, 2015
https://doi.org/10.1371/journal.pone.0123385

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