Interleukin-15 Dendritic Cells Harness NK Cell Cytotoxic Effector Function in a Contact- and IL-15-Dependent Manner

Sébastien Anguille; Heleen H. Van Acker; Johan Van den Bergh; Yannick Willemen; Herman Goossens; Viggo F. Van Tendeloo; Evelien L. Smits; Zwi N. Berneman; Eva Lion

doi:10.1371/journal.pone.0123340

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Peer-reviewed

Research Article

Interleukin-15 Dendritic Cells Harness NK Cell Cytotoxic Effector Function in a Contact- and IL-15-Dependent Manner

Sébastien Anguille ,

Contributed equally to this work with: Sébastien Anguille, Heleen H. Van Acker

* E-mail: sebastien.anguille@uantwerp.be

Affiliations Laboratory of Experimental Hematology, Tumor Immunology Group (TIGR), Vaccine & Infectious Disease Institute (VAXINFECTIO), University of Antwerp, Faculty of Medicine and Health Sciences, Antwerp, Belgium, Center for Cell Therapy & Regenerative Medicine, Antwerp University Hospital, Edegem, Belgium
⨯
Heleen H. Van Acker ,

Contributed equally to this work with: Sébastien Anguille, Heleen H. Van Acker

Affiliation Laboratory of Experimental Hematology, Tumor Immunology Group (TIGR), Vaccine & Infectious Disease Institute (VAXINFECTIO), University of Antwerp, Faculty of Medicine and Health Sciences, Antwerp, Belgium
⨯
Johan Van den Bergh,

Affiliation Laboratory of Experimental Hematology, Tumor Immunology Group (TIGR), Vaccine & Infectious Disease Institute (VAXINFECTIO), University of Antwerp, Faculty of Medicine and Health Sciences, Antwerp, Belgium
⨯
Yannick Willemen,

Affiliation Laboratory of Experimental Hematology, Tumor Immunology Group (TIGR), Vaccine & Infectious Disease Institute (VAXINFECTIO), University of Antwerp, Faculty of Medicine and Health Sciences, Antwerp, Belgium
⨯
Herman Goossens,

Affiliation Laboratory of Experimental Hematology, Tumor Immunology Group (TIGR), Vaccine & Infectious Disease Institute (VAXINFECTIO), University of Antwerp, Faculty of Medicine and Health Sciences, Antwerp, Belgium
⨯
Viggo F. Van Tendeloo,

Affiliation Laboratory of Experimental Hematology, Tumor Immunology Group (TIGR), Vaccine & Infectious Disease Institute (VAXINFECTIO), University of Antwerp, Faculty of Medicine and Health Sciences, Antwerp, Belgium
⨯
Evelien L. Smits,

Affiliations Center for Cell Therapy & Regenerative Medicine, Antwerp University Hospital, Edegem, Belgium, Center for Oncological Research, University of Antwerp, Faculty of Medicine and Health Sciences, Antwerp, Belgium
⨯
Zwi N. Berneman,

Affiliations Laboratory of Experimental Hematology, Tumor Immunology Group (TIGR), Vaccine & Infectious Disease Institute (VAXINFECTIO), University of Antwerp, Faculty of Medicine and Health Sciences, Antwerp, Belgium, Center for Cell Therapy & Regenerative Medicine, Antwerp University Hospital, Edegem, Belgium
⨯
Eva Lion

Affiliation Laboratory of Experimental Hematology, Tumor Immunology Group (TIGR), Vaccine & Infectious Disease Institute (VAXINFECTIO), University of Antwerp, Faculty of Medicine and Health Sciences, Antwerp, Belgium
⨯

Interleukin-15 Dendritic Cells Harness NK Cell Cytotoxic Effector Function in a Contact- and IL-15-Dependent Manner

Sébastien Anguille,
Heleen H. Van Acker,
Johan Van den Bergh,
Yannick Willemen,
Herman Goossens,
Viggo F. Van Tendeloo,
Evelien L. Smits,
Zwi N. Berneman,
Eva Lion

Published: May 7, 2015
https://doi.org/10.1371/journal.pone.0123340

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