Human Induced Hepatic Lineage-Oriented Stem Cells: Autonomous Specification of Human iPS Cells toward Hepatocyte-Like Cells without Any Exogenous Differentiation Factors

• Tetsuya Ishikawa ,

  Contributed equally to this work with: Tetsuya Ishikawa, Momoko Kobayashi

  * E-mail: teishika@ncc.go.jp

  Affiliation Core Facilities for Research and Innovative Medicine, National Cancer Center Research Institute, Chuo-ku, Tokyo, Japan

  ⨯
• Momoko Kobayashi ,

  Contributed equally to this work with: Tetsuya Ishikawa, Momoko Kobayashi

  Affiliation Core Facilities for Research and Innovative Medicine, National Cancer Center Research Institute, Chuo-ku, Tokyo, Japan

  ⨯
• Satoshi Yanagi,

  Affiliation Takara Bio, Inc., Otsu, Shiga, Japan

  ⨯
• Chika Kato,

  Affiliation Takara Bio, Inc., Otsu, Shiga, Japan

  ⨯
• Ryokichi Takashima,

  Affiliation Takara Bio, Inc., Otsu, Shiga, Japan

  ⨯
• Eiji Kobayashi,

  Affiliation Takara Bio, Inc., Otsu, Shiga, Japan

  ⨯
• Keitaro Hagiwara,

  Affiliation Division of Molecular and Cellular Medicine, National Cancer Center Research Institute, Chuo-ku, Tokyo, Japan

  ⨯
• Takahiro Ochiya

  Affiliation Division of Molecular and Cellular Medicine, National Cancer Center Research Institute, Chuo-ku, Tokyo, Japan

  ⨯