Serotonin Transporter Gene Polymorphism Modulates Activity and Connectivity within an Emotional Arousal Network of Healthy Men during an Aversive Visceral Stimulus

Lisa A. Kilpatrick; Emeran A. Mayer; Jennifer S. Labus; Arpana Gupta; Toyohiro Hamaguchi; Tomoko Mizuno; Hazuki Komuro; Michiko Kano; Motoyori Kanazawa; Masashi Aoki; Shin Fukudo

doi:10.1371/journal.pone.0123183

Loading metrics

Open Access

Peer-reviewed

Research Article

Serotonin Transporter Gene Polymorphism Modulates Activity and Connectivity within an Emotional Arousal Network of Healthy Men during an Aversive Visceral Stimulus

Lisa A. Kilpatrick ,

Contributed equally to this work with: Lisa A. Kilpatrick, Emeran A. Mayer

Affiliation Oppenheimer Family Center for Neurobiology of Stress, Division of Digestive Diseases, David Geffen School of Medicine at University of California at Los Angeles (UCLA), Los Angeles, California, United States of America
⨯
Emeran A. Mayer ,

Contributed equally to this work with: Lisa A. Kilpatrick, Emeran A. Mayer

Affiliation Oppenheimer Family Center for Neurobiology of Stress, Division of Digestive Diseases, David Geffen School of Medicine at University of California at Los Angeles (UCLA), Los Angeles, California, United States of America
⨯
Jennifer S. Labus,

Affiliation Oppenheimer Family Center for Neurobiology of Stress, Division of Digestive Diseases, David Geffen School of Medicine at University of California at Los Angeles (UCLA), Los Angeles, California, United States of America
⨯
Arpana Gupta,

Affiliation Oppenheimer Family Center for Neurobiology of Stress, Division of Digestive Diseases, David Geffen School of Medicine at University of California at Los Angeles (UCLA), Los Angeles, California, United States of America
⨯
Toyohiro Hamaguchi,

Affiliation Department of Behavioral Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan
⨯
Tomoko Mizuno,

Affiliation Department of Behavioral Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan
⨯
Hazuki Komuro,

Affiliation Department of Behavioral Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan
⨯
Michiko Kano,

Affiliation Department of Behavioral Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan
⨯
Motoyori Kanazawa,

Affiliations Department of Behavioral Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan, Department of Psychosomatic Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan
⨯
Masashi Aoki,

Affiliation Department of Neurology, Tohoku University Graduate School of Medicine, Sendai, Japan
⨯
Shin Fukudo

* E-mail: sfukudo@med.tohoku.ac.jp

Affiliations Department of Behavioral Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan, Department of Psychosomatic Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan
⨯

Serotonin Transporter Gene Polymorphism Modulates Activity and Connectivity within an Emotional Arousal Network of Healthy Men during an Aversive Visceral Stimulus

Lisa A. Kilpatrick,
Emeran A. Mayer,
Jennifer S. Labus,
Arpana Gupta,
Toyohiro Hamaguchi,
Tomoko Mizuno,
Hazuki Komuro,
Michiko Kano,
Motoyori Kanazawa,
Masashi Aoki

Published: April 20, 2015
https://doi.org/10.1371/journal.pone.0123183

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Serotonin
Is the Subject Area "Serotonin" applicable to this article?

Thanks for your feedback.
Amygdala
Is the Subject Area "Amygdala" applicable to this article?

Thanks for your feedback.
Hippocampus
Is the Subject Area "Hippocampus" applicable to this article?

Thanks for your feedback.
Emotions
Is the Subject Area "Emotions" applicable to this article?

Thanks for your feedback.
Prefrontal cortex
Is the Subject Area "Prefrontal cortex" applicable to this article?

Thanks for your feedback.
Cingulate cortex
Is the Subject Area "Cingulate cortex" applicable to this article?

Thanks for your feedback.
Fear
Is the Subject Area "Fear" applicable to this article?

Thanks for your feedback.
Variant genotypes
Is the Subject Area "Variant genotypes" applicable to this article?

Thanks for your feedback.