HPLC-DAD-ELSD Combined Pharmacodynamics and Serum Medicinal Chemistry for Quality Assessment of Huangqi Granule

Huaguo Chen; Xin Zhou; Yang Zhao; Xiao-Jian Gong; Yan He; Feng-Wei Ma; Mei Zhou; Chao Zhao; Yi Niu; Jie Deng

doi:10.1371/journal.pone.0123176

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Peer-reviewed

Research Article

HPLC-DAD-ELSD Combined Pharmacodynamics and Serum Medicinal Chemistry for Quality Assessment of Huangqi Granule

Huaguo Chen ,

Contributed equally to this work with: Huaguo Chen, Xin Zhou

Affiliations Guizhou Engineering Laboratory for Quality Control & Evaluation Technology of Medicine, Guiyang, Guizhou, P. R. China, The Research Center for Quality Control of Natural Medicine, Guizhou Normal University, Guiyang, Guizhou, P. R. China, Key laboratory for Information System of Mountainous Areas and Protection of Ecological Environment, Guizhou Normal University, Guiyang, Guizhou, P. R. China
⨯
Xin Zhou ,

Contributed equally to this work with: Huaguo Chen, Xin Zhou

* E-mail: 642452984@qq.com

Affiliations Guizhou Engineering Laboratory for Quality Control & Evaluation Technology of Medicine, Guiyang, Guizhou, P. R. China, The Research Center for Quality Control of Natural Medicine, Guizhou Normal University, Guiyang, Guizhou, P. R. China, Key laboratory for Information System of Mountainous Areas and Protection of Ecological Environment, Guizhou Normal University, Guiyang, Guizhou, P. R. China
⨯
Yang Zhao,

Affiliations Guizhou Engineering Laboratory for Quality Control & Evaluation Technology of Medicine, Guiyang, Guizhou, P. R. China, The Research Center for Quality Control of Natural Medicine, Guizhou Normal University, Guiyang, Guizhou, P. R. China, Key laboratory for Information System of Mountainous Areas and Protection of Ecological Environment, Guizhou Normal University, Guiyang, Guizhou, P. R. China
⨯
Xiao-Jian Gong,

Affiliations Guizhou Engineering Laboratory for Quality Control & Evaluation Technology of Medicine, Guiyang, Guizhou, P. R. China, The Research Center for Quality Control of Natural Medicine, Guizhou Normal University, Guiyang, Guizhou, P. R. China, Key laboratory for Information System of Mountainous Areas and Protection of Ecological Environment, Guizhou Normal University, Guiyang, Guizhou, P. R. China
⨯
Yan He,

Affiliations Guizhou Engineering Laboratory for Quality Control & Evaluation Technology of Medicine, Guiyang, Guizhou, P. R. China, The Research Center for Quality Control of Natural Medicine, Guizhou Normal University, Guiyang, Guizhou, P. R. China, Key laboratory for Information System of Mountainous Areas and Protection of Ecological Environment, Guizhou Normal University, Guiyang, Guizhou, P. R. China
⨯
Feng-Wei Ma,

Affiliations Guizhou Engineering Laboratory for Quality Control & Evaluation Technology of Medicine, Guiyang, Guizhou, P. R. China, The Research Center for Quality Control of Natural Medicine, Guizhou Normal University, Guiyang, Guizhou, P. R. China, Key laboratory for Information System of Mountainous Areas and Protection of Ecological Environment, Guizhou Normal University, Guiyang, Guizhou, P. R. China
⨯
Mei Zhou,

Affiliations Guizhou Engineering Laboratory for Quality Control & Evaluation Technology of Medicine, Guiyang, Guizhou, P. R. China, The Research Center for Quality Control of Natural Medicine, Guizhou Normal University, Guiyang, Guizhou, P. R. China, Key laboratory for Information System of Mountainous Areas and Protection of Ecological Environment, Guizhou Normal University, Guiyang, Guizhou, P. R. China
⨯
Chao Zhao,

Affiliations Guizhou Engineering Laboratory for Quality Control & Evaluation Technology of Medicine, Guiyang, Guizhou, P. R. China, The Research Center for Quality Control of Natural Medicine, Guizhou Normal University, Guiyang, Guizhou, P. R. China, Key laboratory for Information System of Mountainous Areas and Protection of Ecological Environment, Guizhou Normal University, Guiyang, Guizhou, P. R. China
⨯
Yi Niu,

Affiliation Han Fang Pharmaceutical co., LTD of Guizhou province, Guiyang, Guizhou, P. R. China
⨯
Jie Deng

Affiliation Han Fang Pharmaceutical co., LTD of Guizhou province, Guiyang, Guizhou, P. R. China
⨯

HPLC-DAD-ELSD Combined Pharmacodynamics and Serum Medicinal Chemistry for Quality Assessment of Huangqi Granule

Huaguo Chen,
Xin Zhou,
Yang Zhao,
Xiao-Jian Gong,
Yan He,
Feng-Wei Ma,
Mei Zhou,
Chao Zhao,
Yi Niu,
Jie Deng

Published: April 27, 2015
https://doi.org/10.1371/journal.pone.0123176

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