Calpain Inhibitor PD150606 Attenuates Glutamate Induced Spiral Ganglion Neuron Apoptosis through Apoptosis Inducing Factor Pathway In Vitro

Zhong-Jia Ding; Xin Chen; Xiao-Xu Tang; Xi Wang; Yong-Li Song; Xiao-Dong Chen; Wen-Juan Mi; Jian Wang; Ying Lin; Fu-Quan Chen; Jian-Hua Qiu

doi:10.1371/journal.pone.0123130

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Open Access

Peer-reviewed

Research Article

Calpain Inhibitor PD150606 Attenuates Glutamate Induced Spiral Ganglion Neuron Apoptosis through Apoptosis Inducing Factor Pathway In Vitro

Zhong-Jia Ding ,

Contributed equally to this work with: Zhong-Jia Ding, Xin Chen, Xiao-Xu Tang, Xi Wang

Affiliation Department of Otolaryngology-Head and Neck Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, China
⨯
Xin Chen ,

Contributed equally to this work with: Zhong-Jia Ding, Xin Chen, Xiao-Xu Tang, Xi Wang

Affiliation Department of Otolaryngology-Head and Neck Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, China
⨯
Xiao-Xu Tang ,

Contributed equally to this work with: Zhong-Jia Ding, Xin Chen, Xiao-Xu Tang, Xi Wang

Affiliation Outpatient Department of Logistics Academy, Beijing, China
⨯
Xi Wang ,

Contributed equally to this work with: Zhong-Jia Ding, Xin Chen, Xiao-Xu Tang, Xi Wang

Affiliation Department of Otolaryngology-Head and Neck Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, China
⨯
Yong-Li Song,

Affiliation Department of Otolaryngology-Head and Neck Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, China
⨯
Xiao-Dong Chen,

Affiliation Department of Otolaryngology-Head and Neck Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, China
⨯
Wen-Juan Mi,

Affiliation Department of Otolaryngology-Head and Neck Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, China
⨯
Jian Wang,

Affiliation Department of Otolaryngology-Head and Neck Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, China
⨯
Ying Lin,

Affiliation Department of Otolaryngology-Head and Neck Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, China
⨯
Fu-Quan Chen ,

* E-mail: qiujh@fmmu.edu.cn (JHQ); Chenfq2@yahoo.com (FQC)

Affiliation Department of Otolaryngology-Head and Neck Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, China
⨯
Jian-Hua Qiu

* E-mail: qiujh@fmmu.edu.cn (JHQ); Chenfq2@yahoo.com (FQC)

Affiliation Department of Otolaryngology-Head and Neck Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, China
⨯

Calpain Inhibitor PD150606 Attenuates Glutamate Induced Spiral Ganglion Neuron Apoptosis through Apoptosis Inducing Factor Pathway In Vitro

Zhong-Jia Ding,
Xin Chen,
Xiao-Xu Tang,
Xi Wang,
Yong-Li Song,
Xiao-Dong Chen,
Wen-Juan Mi,
Jian Wang,
Ying Lin,
Fu-Quan Chen

Published: April 15, 2015
https://doi.org/10.1371/journal.pone.0123130

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