Methylene Blue Protects Astrocytes against Glucose Oxygen Deprivation by Improving Cellular Respiration

Gourav Roy Choudhury; Ali Winters; Ryan M. Rich; Myoung-Gwi Ryou; Zygmunt Gryczynski; Fang Yuan; Shao-Hua Yang; Ran Liu

doi:10.1371/journal.pone.0123096

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Peer-reviewed

Research Article

Methylene Blue Protects Astrocytes against Glucose Oxygen Deprivation by Improving Cellular Respiration

Gourav Roy Choudhury,

Affiliation Department of Pharmacology and Neuroscience, Institute for Aging and Alzheimer’s Disease Research, University of North Texas Health Science Center, Fort Worth, Texas, United States of America
⨯
Ali Winters,

Affiliation Department of Pharmacology and Neuroscience, Institute for Aging and Alzheimer’s Disease Research, University of North Texas Health Science Center, Fort Worth, Texas, United States of America
⨯
Ryan M. Rich,

Affiliation Department of Cell Biology & Immunology, University of North Texas Health Science Center, Fort Worth, Texas, United States of America
⨯
Myoung-Gwi Ryou,

Affiliation Department of Pharmacology and Neuroscience, Institute for Aging and Alzheimer’s Disease Research, University of North Texas Health Science Center, Fort Worth, Texas, United States of America
⨯
Zygmunt Gryczynski,

Affiliation Department of Cell Biology & Immunology, University of North Texas Health Science Center, Fort Worth, Texas, United States of America
⨯
Fang Yuan,

Affiliation Department of Neurosurgery, Beijing Tiantan Hospital, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China
⨯
Shao-Hua Yang ,

* E-mail: ran.liu@unthsc.edu (RL); shaohua.yang@unthsc.edu (SY)

Affiliations Department of Pharmacology and Neuroscience, Institute for Aging and Alzheimer’s Disease Research, University of North Texas Health Science Center, Fort Worth, Texas, United States of America, Department of Neurosurgery, Beijing Tiantan Hospital, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China
⨯
Ran Liu

* E-mail: ran.liu@unthsc.edu (RL); shaohua.yang@unthsc.edu (SY)

Affiliation Department of Pharmacology and Neuroscience, Institute for Aging and Alzheimer’s Disease Research, University of North Texas Health Science Center, Fort Worth, Texas, United States of America
⨯

Methylene Blue Protects Astrocytes against Glucose Oxygen Deprivation by Improving Cellular Respiration

Gourav Roy Choudhury,
Ali Winters,
Ryan M. Rich,
Myoung-Gwi Ryou,
Zygmunt Gryczynski,
Fang Yuan,
Shao-Hua Yang,
Ran Liu

Published: April 7, 2015
https://doi.org/10.1371/journal.pone.0123096

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Methylene blue
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