Potential Role of Notch Signalling in CD34+ Chronic Myeloid Leukaemia Cells: Cross-Talk between Notch and BCR-ABL

Abdullah Aljedai; Anne-Marie Buckle; Prashant Hiwarkar; Farhatullah Syed

doi:10.1371/journal.pone.0123016

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Open Access

Peer-reviewed

Research Article

Potential Role of Notch Signalling in CD34⁺ Chronic Myeloid Leukaemia Cells: Cross-Talk between Notch and BCR-ABL

Abdullah Aljedai ,

* E-mail: aaljedai@ksu.edu.sa

Current Address: Current address: Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Saud University, Kingdom of Saudi Arabia

Affiliation Faculty of Life Sciences, Manchester Institute of Biotechnology (MIB), University of Manchester, Manchester, United Kingdom
⨯
Anne-Marie Buckle †,

† Deceased.

Affiliation Faculty of Life Sciences, Manchester Institute of Biotechnology (MIB), University of Manchester, Manchester, United Kingdom
⨯
Prashant Hiwarkar,

Current address: Molecular and Cellular Immunology Section, Department of Infection, Immunity and Inflammation, Institute of Child Health (ICH), University College London (UCL), London, United Kingdom

Affiliation Department of Paediatric Haematology, Great Ormond Street Hospital (GOSH), London, United Kingdom
⨯
Farhatullah Syed

Current Address: Current address: Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Saud University, Kingdom of Saudi Arabia; Molecular and Cellular Immunology Section, Department of Infection, Immunity and Inflammation, Institute of Child Health (ICH), University College London (UCL), London, United Kingdom

Affiliations Faculty of Life Sciences, Manchester Institute of Biotechnology (MIB), University of Manchester, Manchester, United Kingdom, Institute of Inflammation and Repair, Manchester Institute of Biotechnology (MIB), University of Manchester, Manchester, United Kingdom
⨯

Potential Role of Notch Signalling in CD34⁺ Chronic Myeloid Leukaemia Cells: Cross-Talk between Notch and BCR-ABL

Abdullah Aljedai,
Anne-Marie Buckle,
Prashant Hiwarkar,
Farhatullah Syed

Published: April 7, 2015
https://doi.org/10.1371/journal.pone.0123016

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Notch signaling
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Gene expression
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Signal inhibition
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Leukemia
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Polymerase chain reaction
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Primary cells
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Cell staining
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Stem cells
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