Comparative Whole-Genome Analysis of Clinical Isolates Reveals Characteristic Architecture of Mycobacterium tuberculosis Pangenome

Vinita Periwal; Ashok Patowary; Shamsudheen Karuthedath Vellarikkal; Anju Gupta; Meghna Singh; Ashish Mittal; Shamini Jeyapaul; Rajendra Kumar Chauhan; Ajay Vir Singh; Pravin Kumar Singh; Parul Garg; Viswa Mohan Katoch; Kiran Katoch; Devendra Singh Chauhan; Sridhar Sivasubbu; Vinod Scaria

doi:10.1371/journal.pone.0122979

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Peer-reviewed

Research Article

Comparative Whole-Genome Analysis of Clinical Isolates Reveals Characteristic Architecture of Mycobacterium tuberculosis Pangenome

Vinita Periwal,

Affiliations GN Ramachandran Knowledge Center for Genome Informatics, CSIR Institute of Genomics and Integrative Biology (CSIR-IGIB), Mall Road, Delhi—110007, India, Academy of Scientific & Innovative Research (AcSIR), 2, Rafi Marg, Anusandhan Bhawan, New Delhi 110001, India
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Ashok Patowary,

Affiliation Genomics and Molecular Medicine, CSIR Institute of Genomics and Integrative Biology (CSIR-IGIB), Mall Road, Delhi—110007, India
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Shamsudheen Karuthedath Vellarikkal,

Affiliations Genomics and Molecular Medicine, CSIR Institute of Genomics and Integrative Biology (CSIR-IGIB), Mall Road, Delhi—110007, India, Academy of Scientific & Innovative Research (AcSIR), 2, Rafi Marg, Anusandhan Bhawan, New Delhi 110001, India
⨯
Anju Gupta,

Affiliation Open Source Drug Discovery Unit, Council of Scientific and Industrial Research (CSIR), Anusandhan Bhavan, 2 Rafi Marg, New Delhi 110001, India
⨯
Meghna Singh,

Affiliations Genomics and Molecular Medicine, CSIR Institute of Genomics and Integrative Biology (CSIR-IGIB), Mall Road, Delhi—110007, India, Academy of Scientific & Innovative Research (AcSIR), 2, Rafi Marg, Anusandhan Bhawan, New Delhi 110001, India
⨯
Ashish Mittal,

Affiliation Genomics and Molecular Medicine, CSIR Institute of Genomics and Integrative Biology (CSIR-IGIB), Mall Road, Delhi—110007, India
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Shamini Jeyapaul,

Affiliation Genomics and Molecular Medicine, CSIR Institute of Genomics and Integrative Biology (CSIR-IGIB), Mall Road, Delhi—110007, India
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Rajendra Kumar Chauhan,

Affiliation Genomics and Molecular Medicine, CSIR Institute of Genomics and Integrative Biology (CSIR-IGIB), Mall Road, Delhi—110007, India
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Ajay Vir Singh,

Affiliation National JALMA Institute of Leprosy and other Mycobacterial Diseases, Post Box No.101,Tajganj, Agra-282001, India
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Pravin Kumar Singh,

Affiliation National JALMA Institute of Leprosy and other Mycobacterial Diseases, Post Box No.101,Tajganj, Agra-282001, India
⨯
Parul Garg,

Affiliation National JALMA Institute of Leprosy and other Mycobacterial Diseases, Post Box No.101,Tajganj, Agra-282001, India
⨯
Viswa Mohan Katoch,

Affiliation National JALMA Institute of Leprosy and other Mycobacterial Diseases, Post Box No.101,Tajganj, Agra-282001, India
⨯
Kiran Katoch,

Affiliation National JALMA Institute of Leprosy and other Mycobacterial Diseases, Post Box No.101,Tajganj, Agra-282001, India
⨯
Devendra Singh Chauhan,

Affiliation National JALMA Institute of Leprosy and other Mycobacterial Diseases, Post Box No.101,Tajganj, Agra-282001, India
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Sridhar Sivasubbu ,

* E-mail: vinods@igib.in (VS); sridhar@igib.in (SS)

Affiliation Genomics and Molecular Medicine, CSIR Institute of Genomics and Integrative Biology (CSIR-IGIB), Mall Road, Delhi—110007, India
⨯
[ ... ],
Vinod Scaria

* E-mail: vinods@igib.in (VS); sridhar@igib.in (SS)

Affiliation GN Ramachandran Knowledge Center for Genome Informatics, CSIR Institute of Genomics and Integrative Biology (CSIR-IGIB), Mall Road, Delhi—110007, India
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Comparative Whole-Genome Analysis of Clinical Isolates Reveals Characteristic Architecture of Mycobacterium tuberculosis Pangenome

Vinita Periwal,
Ashok Patowary,
Shamsudheen Karuthedath Vellarikkal,
Anju Gupta,
Meghna Singh,
Ashish Mittal,
Shamini Jeyapaul,
Rajendra Kumar Chauhan,
Ajay Vir Singh,
Pravin Kumar Singh

Published: April 8, 2015
https://doi.org/10.1371/journal.pone.0122979

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