Elevated High-Sensitivity C-Reactive Protein Levels Predict Decreased Survival for Nasopharyngeal Carcinoma Patients in the Intensity-Modulated Radiotherapy Era

Lin Quan Tang; Dong Peng Hu; Qiu Yan Chen; Lu Zhang; Xiao Ping Lai; Yun He; Yun-Xiu-Xiu Xu; Shi-Hua Wen; Yu-Tuan Peng; Wen-Hui Chen; Shan-Shan Guo; Li-Ting Liu; Chao-Nan Qian; Xiang Guo; Mu-Sheng Zeng; Hai-Qiang Mai

doi:10.1371/journal.pone.0122965

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Peer-reviewed

Research Article

Elevated High-Sensitivity C-Reactive Protein Levels Predict Decreased Survival for Nasopharyngeal Carcinoma Patients in the Intensity-Modulated Radiotherapy Era

Lin Quan Tang ,

Contributed equally to this work with: Lin Quan Tang, Dong Peng Hu

Affiliations State Key Laboratory of Oncology in South China and Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China, Department of Nasopharyngeal Carcinoma, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China
⨯
Dong Peng Hu ,

Contributed equally to this work with: Lin Quan Tang, Dong Peng Hu

Affiliation ZhongShan School of Medicine, Sun Yat-sen University, Guangzhou, Guangdong, China
⨯
Qiu Yan Chen,

Affiliations State Key Laboratory of Oncology in South China and Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China, Department of Nasopharyngeal Carcinoma, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China
⨯
Lu Zhang,

Affiliations State Key Laboratory of Oncology in South China and Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China, Department of Nasopharyngeal Carcinoma, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China
⨯
Xiao Ping Lai,

Affiliation ZhongShan School of Medicine, Sun Yat-sen University, Guangzhou, Guangdong, China
⨯
Yun He,

Affiliation ZhongShan School of Medicine, Sun Yat-sen University, Guangzhou, Guangdong, China
⨯
Yun-Xiu-Xiu Xu,

Affiliation ZhongShan School of Medicine, Sun Yat-sen University, Guangzhou, Guangdong, China
⨯
Shi-Hua Wen,

Affiliation ZhongShan School of Medicine, Sun Yat-sen University, Guangzhou, Guangdong, China
⨯
Yu-Tuan Peng,

Affiliation ZhongShan School of Medicine, Sun Yat-sen University, Guangzhou, Guangdong, China
⨯
Wen-Hui Chen,

Affiliation State Key Laboratory of Oncology in South China and Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China
⨯
Shan-Shan Guo,

Affiliations State Key Laboratory of Oncology in South China and Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China, Department of Nasopharyngeal Carcinoma, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China
⨯
Li-Ting Liu,

Affiliations State Key Laboratory of Oncology in South China and Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China, Department of Nasopharyngeal Carcinoma, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China
⨯
Chao-Nan Qian,

Affiliations State Key Laboratory of Oncology in South China and Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China, Department of Nasopharyngeal Carcinoma, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China
⨯
Xiang Guo,

Affiliations State Key Laboratory of Oncology in South China and Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China, Department of Nasopharyngeal Carcinoma, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China
⨯
Mu-Sheng Zeng ,

* E-mail: zengmsh@mail.sysu.edu.cn (MSZ); maihq@mail.sysu.edu.cn (HQM)

Affiliations State Key Laboratory of Oncology in South China and Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China, Department of Nasopharyngeal Carcinoma, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China
⨯
[ ... ],
Hai-Qiang Mai

* E-mail: zengmsh@mail.sysu.edu.cn (MSZ); maihq@mail.sysu.edu.cn (HQM)

Affiliations State Key Laboratory of Oncology in South China and Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China, Department of Nasopharyngeal Carcinoma, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China
⨯
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Elevated High-Sensitivity C-Reactive Protein Levels Predict Decreased Survival for Nasopharyngeal Carcinoma Patients in the Intensity-Modulated Radiotherapy Era

Lin Quan Tang,
Dong Peng Hu,
Qiu Yan Chen,
Lu Zhang,
Xiao Ping Lai,
Yun He,
Yun-Xiu-Xiu Xu,
Shi-Hua Wen,
Yu-Tuan Peng,
Wen-Hui Chen

Published: April 13, 2015
https://doi.org/10.1371/journal.pone.0122965

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