BMP9 Crosstalk with the Hippo Pathway Regulates Endothelial Cell Matricellular and Chemokine Responses

Kira Young; Eric Tweedie; Barbara Conley; Jacquelyn Ames; MaryLynn FitzSimons; Peter Brooks; Lucy Liaw; Calvin P. H. Vary

doi:10.1371/journal.pone.0122892

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Peer-reviewed

Research Article

BMP9 Crosstalk with the Hippo Pathway Regulates Endothelial Cell Matricellular and Chemokine Responses

Kira Young,

Current address: The Jackson Laboratory, Bar Harbor, Maine 04609, United States of America

Affiliations Center for Molecular Medicine, Maine Medical Center Research Institute, Scarborough, Maine 04074, United States of America, Graduate School of Biomedical Sciences and Engineering, University of Maine, Orono, Maine 04469, United States of America
⨯
Eric Tweedie,

Affiliation Center for Molecular Medicine, Maine Medical Center Research Institute, Scarborough, Maine 04074, United States of America
⨯
Barbara Conley,

Affiliation Center for Molecular Medicine, Maine Medical Center Research Institute, Scarborough, Maine 04074, United States of America
⨯
Jacquelyn Ames,

Affiliations Center for Molecular Medicine, Maine Medical Center Research Institute, Scarborough, Maine 04074, United States of America, Graduate School of Biomedical Sciences and Engineering, University of Maine, Orono, Maine 04469, United States of America
⨯
MaryLynn FitzSimons,

Affiliation Graduate School of Biomedical Sciences and Engineering, University of Maine, Orono, Maine 04469, United States of America
⨯
Peter Brooks,

Affiliations Center for Molecular Medicine, Maine Medical Center Research Institute, Scarborough, Maine 04074, United States of America, Graduate School of Biomedical Sciences and Engineering, University of Maine, Orono, Maine 04469, United States of America
⨯
Lucy Liaw,

Affiliations Center for Molecular Medicine, Maine Medical Center Research Institute, Scarborough, Maine 04074, United States of America, Graduate School of Biomedical Sciences and Engineering, University of Maine, Orono, Maine 04469, United States of America
⨯
Calvin P. H. Vary

* E-mail: varyc@mmc.org

Affiliations Center for Molecular Medicine, Maine Medical Center Research Institute, Scarborough, Maine 04074, United States of America, Graduate School of Biomedical Sciences and Engineering, University of Maine, Orono, Maine 04469, United States of America
⨯

BMP9 Crosstalk with the Hippo Pathway Regulates Endothelial Cell Matricellular and Chemokine Responses

Kira Young,
Eric Tweedie,
Barbara Conley,
Jacquelyn Ames,
MaryLynn FitzSimons,
Peter Brooks,
Lucy Liaw,
Calvin P. H. Vary

Published: April 24, 2015
https://doi.org/10.1371/journal.pone.0122892

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Endothelial cells
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Focal adhesions
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SMAD signaling
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Inflammation
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Extracellular matrix signaling
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Immunofluorescence
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Integrins
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