MK591, a Second Generation Leukotriene Biosynthesis Inhibitor, Prevents Invasion and Induces Apoptosis in the Bone-Invading C4-2B Human Prostate Cancer Cells: Implications for the Treatment of Castration-Resistant, Bone-Metastatic Prostate Cancer

Open Access

Peer-reviewed

Research Article

Sivalokanathan Sarveswaran,

Affiliation Department of Urology, Henry Ford Health System, Detroit, MI 48202, United States of America
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Ritisha Ghosh,

Affiliation Department of Urology, Henry Ford Health System, Detroit, MI 48202, United States of America
⨯
Shravan Morisetty,

Affiliation Department of Urology, Henry Ford Health System, Detroit, MI 48202, United States of America
⨯
Jagadananda Ghosh

* E-mail: jghosh1@hfhs.org

Affiliations Department of Urology, Henry Ford Health System, Detroit, MI 48202, United States of America, Josephine Ford Cancer Center, Henry Ford Health System, Detroit, MI 48202, United States of America
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Prostate cancer
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Cancer treatment
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Apoptosis
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Metastasis
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Computer software
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Cell metabolism
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Fibroblasts
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Protease inhibitor therapy
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