Gene Editing by Co-Transformation of TALEN and Chimeric RNA/DNA Oligonucleotides on the Rice OsEPSPS Gene and the Inheritance of Mutations

Mugui Wang; Yujun Liu; Cuicui Zhang; Jianping Liu; Xin Liu; Liangchao Wang; Wenyi Wang; Hao Chen; Chuchu Wei; Xiufen Ye; Xinyuan Li; Jumin Tu

doi:10.1371/journal.pone.0122755

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Open Access

Peer-reviewed

Research Article

Gene Editing by Co-Transformation of TALEN and Chimeric RNA/DNA Oligonucleotides on the Rice OsEPSPS Gene and the Inheritance of Mutations

Mugui Wang,

Affiliation Institute of Crop Sciences, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou, Zhejiang Province, China
⨯
Yujun Liu,

Affiliation Institute of Crop Sciences, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou, Zhejiang Province, China
⨯
Cuicui Zhang,

Affiliation Institute of Crop Sciences, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou, Zhejiang Province, China
⨯
Jianping Liu,

Affiliation Institute of Crop Sciences, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou, Zhejiang Province, China
⨯
Xin Liu,

Affiliation Institute of Crop Sciences, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou, Zhejiang Province, China
⨯
Liangchao Wang,

Affiliation Institute of Crop Sciences, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou, Zhejiang Province, China
⨯
Wenyi Wang,

Affiliation Institute of Crop Sciences, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou, Zhejiang Province, China
⨯
Hao Chen,

Affiliation Institute of Crop Sciences, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou, Zhejiang Province, China
⨯
Chuchu Wei,

Affiliation Institute of Crop Sciences, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou, Zhejiang Province, China
⨯
Xiufen Ye,

Affiliation Institute of Crop Sciences, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou, Zhejiang Province, China
⨯
Xinyuan Li,

Affiliation Institute of Crop Sciences, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou, Zhejiang Province, China
⨯
Jumin Tu

* E-mail: jtu@zju.edu.cn

Affiliation Institute of Crop Sciences, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou, Zhejiang Province, China
⨯

Gene Editing by Co-Transformation of TALEN and Chimeric RNA/DNA Oligonucleotides on the Rice OsEPSPS Gene and the Inheritance of Mutations

Mugui Wang,
Yujun Liu,
Cuicui Zhang,
Jianping Liu,
Xin Liu,
Liangchao Wang,
Wenyi Wang,
Hao Chen,
Chuchu Wei,
Xiufen Ye

Published: April 9, 2015
https://doi.org/10.1371/journal.pone.0122755

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TALENs
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Heterozygosity
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Frameshift mutation
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Rice
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Gene targeting
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Homozygosity
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Insertion mutation
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