Streptococcus pneumoniae Induces Autophagy through the Inhibition of the PI3K-I/Akt/mTOR Pathway and ROS Hypergeneration in A549 Cells

Open Access

Peer-reviewed

Research Article

Pu Li,

Affiliation Department of Laboratory medicine, the Second Hospital Affiliated to Chongqing Medical University, Chongqing, China
⨯
Jing Shi,

Affiliation Department of Laboratory medicine, the First Hospital Affiliated to Chongqing Medical University, Chongqing, China
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Qiao He,

Affiliation Department of Laboratory medicine, the Second Hospital Affiliated to Chongqing Medical University, Chongqing, China
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Qin Hu,

Affiliation Department of Laboratory medicine, the Second Hospital Affiliated to Chongqing Medical University, Chongqing, China
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Yun Ying Wang,

Affiliation Department of Laboratory medicine, the Second Hospital Affiliated to Chongqing Medical University, Chongqing, China
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Li Jun Zhang,

Affiliation Department of Laboratory medicine, the Second Hospital Affiliated to Chongqing Medical University, Chongqing, China
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Wai Ting Chan,

Affiliation Centro de Investigaciones Biológicas, Consejo Superior de Investigaciones Científicas, Ramiro de Maeztu 9, Madrid, Spain
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Wei-Xian Chen

* E-mail chenweixian75@163.com

Affiliation Department of Laboratory medicine, the Second Hospital Affiliated to Chongqing Medical University, Chongqing, China
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Autophagic cell death
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Intracellular pathogens
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Bacterial pathogens
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Reactive oxygen species
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Pneumococcus
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Respiratory infections
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Epithelial cells
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Transfection
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