Identification and Functional Analysis of Genome Mutations in a Fluoride-Resistant Streptococcus mutans Strain

Open Access

Peer-reviewed

Research Article

Ying Liao ,

Contributed equally to this work with: Ying Liao, Jianwei Chen

Affiliations State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China, Department of Preventive Dentistry, Academic Centre for Dentistry Amsterdam, University of Amsterdam and VU University Amsterdam, Amsterdam, The Netherlands
⨯
Jianwei Chen ,

Contributed equally to this work with: Ying Liao, Jianwei Chen

Affiliation BGI-Shenzhen, Shenzhen, China
⨯
Bernd Willem Brandt,

Affiliation Department of Preventive Dentistry, Academic Centre for Dentistry Amsterdam, University of Amsterdam and VU University Amsterdam, Amsterdam, The Netherlands
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Yuanfang Zhu,

Affiliation BGI-Shenzhen, Shenzhen, China
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Jiyao Li,

Affiliation State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China
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Cor van Loveren,

Affiliation Department of Preventive Dentistry, Academic Centre for Dentistry Amsterdam, University of Amsterdam and VU University Amsterdam, Amsterdam, The Netherlands
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Dong Mei Deng

* E-mail: d.deng@acta.nl

Affiliation Department of Preventive Dentistry, Academic Centre for Dentistry Amsterdam, University of Amsterdam and VU University Amsterdam, Amsterdam, The Netherlands
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Fluorides
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Streptococcus mutans
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Single nucleotide polymorphisms
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Genomics
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Gene expression
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Pyruvate
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Shotgun sequencing
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Antiport proteins
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