Peptides of Presenilin-1 Bind the Amyloid Precursor Protein Ectodomain and Offer a Novel and Specific Therapeutic Approach to Reduce ß-Amyloid in Alzheimer’s Disease

• Nazneen N. Dewji ,

  * E-mail: ndewji@ucsd.edu

  Affiliations Department of Medicine, University of California San Diego, La Jolla, CA, 92093, United States of America, Cenna Biosciences Incorporated, 505 Coast Boulevard, Suite 302, La Jolla, CA, 92037, United States of America

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• S. Jonathan Singer,

  Affiliations Department of Biology, University of California San Diego, La Jolla, CA, 92093, United States of America, Cenna Biosciences Incorporated, 505 Coast Boulevard, Suite 302, La Jolla, CA, 92037, United States of America

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• Eliezer Masliah,

  Affiliations Department of Neurosciences, University of California San Diego, La Jolla, CA, 92093, United States of America, Department of Pathology, University of California San Diego, La Jolla, CA, 92093, United States of America

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• Edward Rockenstein,

  Affiliation Department of Neurosciences, University of California San Diego, La Jolla, CA, 92093, United States of America

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• Mihyun Kim,

  Affiliations Department of Medicine, University of California San Diego, La Jolla, CA, 92093, United States of America, Cenna Biosciences Incorporated, 505 Coast Boulevard, Suite 302, La Jolla, CA, 92037, United States of America

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• Martha Harber,

  Affiliation FortéBio, Pall Corporation, 1360 Willow Rd, Suite 201, Menlo Park, CA, 94025, United States of America

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• Taylor Horwood

  Affiliation Department of Neuroscience Imaging Core, University of California San Diego, La Jolla, CA, 92093, United States of America

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