The Impact of Immunosenescence on Humoral Immune Response Variation after Influenza A/H1N1 Vaccination in Older Subjects

Iana H. Haralambieva; Scott D. Painter; Richard B. Kennedy; Inna G. Ovsyannikova; Nathaniel D. Lambert; Krista M. Goergen; Ann L. Oberg; Gregory A. Poland

doi:10.1371/journal.pone.0122282

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Peer-reviewed

Research Article

The Impact of Immunosenescence on Humoral Immune Response Variation after Influenza A/H1N1 Vaccination in Older Subjects

Iana H. Haralambieva,

Affiliations Mayo Vaccine Research Group, Mayo Clinic, Rochester, Minnesota, United States of America, Program in Translational Immunovirology and Biodefense, Mayo Clinic, Rochester, Minnesota, United States of America
⨯
Scott D. Painter,

Affiliation Mayo Vaccine Research Group, Mayo Clinic, Rochester, Minnesota, United States of America
⨯
Richard B. Kennedy,

Affiliations Mayo Vaccine Research Group, Mayo Clinic, Rochester, Minnesota, United States of America, Program in Translational Immunovirology and Biodefense, Mayo Clinic, Rochester, Minnesota, United States of America
⨯
Inna G. Ovsyannikova,

Affiliations Mayo Vaccine Research Group, Mayo Clinic, Rochester, Minnesota, United States of America, Program in Translational Immunovirology and Biodefense, Mayo Clinic, Rochester, Minnesota, United States of America
⨯
Nathaniel D. Lambert,

Affiliations Mayo Vaccine Research Group, Mayo Clinic, Rochester, Minnesota, United States of America, Program in Translational Immunovirology and Biodefense, Mayo Clinic, Rochester, Minnesota, United States of America
⨯
Krista M. Goergen,

Affiliations Mayo Vaccine Research Group, Mayo Clinic, Rochester, Minnesota, United States of America, Division of Biomedical Statistics and Informatics - Department of Health Science Research, Mayo Clinic, Rochester, Minnesota, United States of America
⨯
Ann L. Oberg,

Affiliations Mayo Vaccine Research Group, Mayo Clinic, Rochester, Minnesota, United States of America, Division of Biomedical Statistics and Informatics - Department of Health Science Research, Mayo Clinic, Rochester, Minnesota, United States of America
⨯
Gregory A. Poland

* E-mail: poland.gregory@mayo.edu

Affiliations Mayo Vaccine Research Group, Mayo Clinic, Rochester, Minnesota, United States of America, Program in Translational Immunovirology and Biodefense, Mayo Clinic, Rochester, Minnesota, United States of America, Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, Minnesota, United States of America
⨯

The Impact of Immunosenescence on Humoral Immune Response Variation after Influenza A/H1N1 Vaccination in Older Subjects

Iana H. Haralambieva,
Scott D. Painter,
Richard B. Kennedy,
Inna G. Ovsyannikova,
Nathaniel D. Lambert,
Krista M. Goergen,
Ann L. Oberg,
Gregory A. Poland

Published: March 27, 2015
https://doi.org/10.1371/journal.pone.0122282

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