Complement Component C3 and Butyrylcholinesterase Activity Are Associated with Neurodegeneration and Clinical Disability in Multiple Sclerosis

Shahin Aeinehband; Rickard P. F. Lindblom; Faiez Al Nimer; Swetha Vijayaraghavan; Kerstin Sandholm; Mohsen Khademi; Tomas Olsson; Bo Nilsson; Kristina Nilsson Ekdahl; Taher Darreh-Shori; Fredrik Piehl

doi:10.1371/journal.pone.0122048

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Open Access

Peer-reviewed

Research Article

Complement Component C3 and Butyrylcholinesterase Activity Are Associated with Neurodegeneration and Clinical Disability in Multiple Sclerosis

Shahin Aeinehband ,

Contributed equally to this work with: Shahin Aeinehband, Rickard P. F. Lindblom

* E-mail: shahin.aeinehband@ki.se

Affiliation Department of Clinical Neuroscience, Neuroimmunology Unit, Karolinska Institutet, Stockholm, Sweden
⨯
Rickard P. F. Lindblom ,

Contributed equally to this work with: Shahin Aeinehband, Rickard P. F. Lindblom

Affiliation Department of Clinical Neuroscience, Neuroimmunology Unit, Karolinska Institutet, Stockholm, Sweden
⨯
Faiez Al Nimer,

Affiliation Department of Clinical Neuroscience, Neuroimmunology Unit, Karolinska Institutet, Stockholm, Sweden
⨯
Swetha Vijayaraghavan,

Affiliation Division of Alzheimer Neurobiology Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden
⨯
Kerstin Sandholm,

Affiliation School of Natural Sciences, Linnæus University, Kalmar, Sweden
⨯
Mohsen Khademi,

Affiliation Department of Clinical Neuroscience, Neuroimmunology Unit, Karolinska Institutet, Stockholm, Sweden
⨯
Tomas Olsson,

Affiliation Department of Clinical Neuroscience, Neuroimmunology Unit, Karolinska Institutet, Stockholm, Sweden
⨯
Bo Nilsson,

Affiliation Division of Clinical Immunology, Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden
⨯
Kristina Nilsson Ekdahl,

Affiliations Division of Clinical Immunology, Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden, School of Natural Sciences, Linnæus University, Kalmar, Sweden
⨯
Taher Darreh-Shori,

Affiliation Division of Alzheimer Neurobiology Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden
⨯
Fredrik Piehl

Affiliation Department of Clinical Neuroscience, Neuroimmunology Unit, Karolinska Institutet, Stockholm, Sweden
⨯

Complement Component C3 and Butyrylcholinesterase Activity Are Associated with Neurodegeneration and Clinical Disability in Multiple Sclerosis

Shahin Aeinehband,
Rickard P. F. Lindblom,
Faiez Al Nimer,
Swetha Vijayaraghavan,
Kerstin Sandholm,
Mohsen Khademi,
Tomas Olsson,
Bo Nilsson,
Kristina Nilsson Ekdahl,
Taher Darreh-Shori

Published: April 2, 2015
https://doi.org/10.1371/journal.pone.0122048

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Cerebrospinal fluid
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Complement system
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