Tang-Nai-Kang Alleviates Pre-diabetes and Metabolic Disorders and Induces a Gene Expression Switch toward Fatty Acid Oxidation in SHR.Cg-Leprcp/NDmcr Rats

Linyi Li; Hisae Yoshitomi; Ying Wei; Lingling Qin; Jingxin Zhou; Tunhai Xu; Xinli Wu; Tian Zhou; Wen Sun; Xiangyu Guo; Lili Wu; Haiyan Wang; Yan Zhang; Chunna Li; Tonghua Liu; Ming Gao

doi:10.1371/journal.pone.0122024

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Peer-reviewed

Research Article

Tang-Nai-Kang Alleviates Pre-diabetes and Metabolic Disorders and Induces a Gene Expression Switch toward Fatty Acid Oxidation in SHR.Cg-Leprcp/NDmcr Rats

Linyi Li,

Affiliation Health-cultivation Laboratory of the Ministry of Education, Beijing University of Chinese Medicine, Beijing, China
⨯
Hisae Yoshitomi,

Affiliation School of Pharmaceutical Sciences, Mukogawa Women’s University, Hyogo, Japan
⨯
Ying Wei,

Affiliation Health-cultivation Laboratory of the Ministry of Education, Beijing University of Chinese Medicine, Beijing, China
⨯
Lingling Qin,

Affiliation Health-cultivation Laboratory of the Ministry of Education, Beijing University of Chinese Medicine, Beijing, China
⨯
Jingxin Zhou,

Affiliation Dongzhimen Hospital Eastern Affiliated to Beijing University of Chinese Medicine, Beijing, China
⨯
Tunhai Xu,

Affiliation Health-cultivation Laboratory of the Ministry of Education, Beijing University of Chinese Medicine, Beijing, China
⨯
Xinli Wu,

Affiliation Health-cultivation Laboratory of the Ministry of Education, Beijing University of Chinese Medicine, Beijing, China
⨯
Tian Zhou,

Affiliation Dongfang Hospital Affiliated to Beijing University of Chinese Medicine, Beijing, China
⨯
Wen Sun,

Affiliation Health-cultivation Laboratory of the Ministry of Education, Beijing University of Chinese Medicine, Beijing, China
⨯
Xiangyu Guo,

Affiliation Dongfang Hospital Affiliated to Beijing University of Chinese Medicine, Beijing, China
⨯
Lili Wu,

Affiliation Health-cultivation Laboratory of the Ministry of Education, Beijing University of Chinese Medicine, Beijing, China
⨯
Haiyan Wang,

Affiliation Health-cultivation Laboratory of the Ministry of Education, Beijing University of Chinese Medicine, Beijing, China
⨯
Yan Zhang,

Affiliation Health-cultivation Laboratory of the Ministry of Education, Beijing University of Chinese Medicine, Beijing, China
⨯
Chunna Li,

Affiliation Health-cultivation Laboratory of the Ministry of Education, Beijing University of Chinese Medicine, Beijing, China
⨯
Tonghua Liu ,

* E-mail: thliu@vip.163.com (TL); gaoming@mukogawa-u.ac.jp (MG)

Affiliation Health-cultivation Laboratory of the Ministry of Education, Beijing University of Chinese Medicine, Beijing, China
⨯
[ ... ],
Ming Gao

* E-mail: thliu@vip.163.com (TL); gaoming@mukogawa-u.ac.jp (MG)

Affiliation School of Pharmaceutical Sciences, Mukogawa Women’s University, Hyogo, Japan
⨯
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Tang-Nai-Kang Alleviates Pre-diabetes and Metabolic Disorders and Induces a Gene Expression Switch toward Fatty Acid Oxidation in SHR.Cg-Leprcp/NDmcr Rats

Linyi Li,
Hisae Yoshitomi,
Ying Wei,
Lingling Qin,
Jingxin Zhou,
Tunhai Xu,
Xinli Wu,
Tian Zhou,
Wen Sun,
Xiangyu Guo

Published: April 13, 2015
https://doi.org/10.1371/journal.pone.0122024

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Gene expression
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Fatty acids
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Oxidation
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Adipose tissue
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Glucose metabolism
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