Potentiation of Insulin-Mediated Glucose Lowering without Elevated Hypoglycemia Risk by a Small Molecule Insulin Receptor Modulator

Open Access

Peer-reviewed

Research Article

Margaret Wu,

Affiliation Early Development and Discovery Sciences, Merck Research Laboratories, Merck Sharp & Dohme Corp., Whitehouse Station, NJ 08889, United States of America
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Ge Dai,

Affiliation Early Development and Discovery Sciences, Merck Research Laboratories, Merck Sharp & Dohme Corp., Whitehouse Station, NJ 08889, United States of America
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Jun Yao,

Affiliation Early Development and Discovery Sciences, Merck Research Laboratories, Merck Sharp & Dohme Corp., Whitehouse Station, NJ 08889, United States of America
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Scott Hoyt,

Affiliation Early Development and Discovery Sciences, Merck Research Laboratories, Merck Sharp & Dohme Corp., Whitehouse Station, NJ 08889, United States of America
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Liangsu Wang,

Affiliation Early Development and Discovery Sciences, Merck Research Laboratories, Merck Sharp & Dohme Corp., Whitehouse Station, NJ 08889, United States of America
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James Mu

* E-mail: yingjun_mu@merck.com

Affiliation Early Development and Discovery Sciences, Merck Research Laboratories, Merck Sharp & Dohme Corp., Whitehouse Station, NJ 08889, United States of America
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Insulin
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Glucose
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Hypoglycemia
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Diabetes mellitus
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Mouse models
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Insulin signaling
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Glucose signaling
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Sensory perception
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