Comparison of Newly Diagnosed and Relapsed Patients with Acute Promyelocytic Leukemia Treated with Arsenic Trioxide: Insight into Mechanisms of Resistance

Ezhilarasi Chendamarai; Saravanan Ganesan; Ansu Abu Alex; Vandana Kamath; Sukesh C. Nair; Arun Jose Nellickal; Nancy Beryl Janet; Vivi Srivastava; Kavitha M. Lakshmi; Auro Viswabandya; Aby Abraham; Mohammed Aiyaz; Nandita Mullapudi; Raja Mugasimangalam; Rose Ann Padua; Christine Chomienne; Mammen Chandy; Alok Srivastava; Biju George; Poonkuzhali Balasubramanian; Vikram Mathews

doi:10.1371/journal.pone.0121912

Loading metrics

Open Access

Peer-reviewed

Research Article

Comparison of Newly Diagnosed and Relapsed Patients with Acute Promyelocytic Leukemia Treated with Arsenic Trioxide: Insight into Mechanisms of Resistance

Ezhilarasi Chendamarai,

Affiliation Department of Haematology, Christian Medical College, Vellore, India
⨯
Saravanan Ganesan,

Affiliation Department of Haematology, Christian Medical College, Vellore, India
⨯
Ansu Abu Alex,

Affiliation Department of Haematology, Christian Medical College, Vellore, India
⨯
Vandana Kamath,

Affiliation Department of Transfusion Medicine and Immunohaematology, Christian Medical College, Vellore, India
⨯
Sukesh C. Nair,

Affiliation Department of Transfusion Medicine and Immunohaematology, Christian Medical College, Vellore, India
⨯
Arun Jose Nellickal,

Affiliation Department of Biochemistry, Christian Medical College, Vellore, India
⨯
Nancy Beryl Janet,

Affiliation Department of Haematology, Christian Medical College, Vellore, India
⨯
Vivi Srivastava,

Affiliation Cytogenetics Unit, Christian Medical College, Vellore, India
⨯
Kavitha M. Lakshmi,

Affiliation Department of Haematology, Christian Medical College, Vellore, India
⨯
Auro Viswabandya,

Affiliation Department of Haematology, Christian Medical College, Vellore, India
⨯
Aby Abraham,

Affiliation Department of Haematology, Christian Medical College, Vellore, India
⨯
Mohammed Aiyaz,

Affiliation Genotypic Technology, Bengaluru, India
⨯
Nandita Mullapudi,

Affiliation Genotypic Technology, Bengaluru, India
⨯
Raja Mugasimangalam,

Affiliation Genotypic Technology, Bengaluru, India
⨯
Rose Ann Padua,

Affiliation UMR 1131 Institut d’Hématologie, Hôpital Saint Louis, I avenue Claude Vellefaux, 75010 Paris, France
⨯
Christine Chomienne,

Affiliation UMR 1131 Institut d’Hématologie, Hôpital Saint Louis, I avenue Claude Vellefaux, 75010 Paris, France
⨯
Mammen Chandy,

Affiliation Department of Haematology, Christian Medical College, Vellore, India
⨯
Alok Srivastava,

Affiliation Department of Haematology, Christian Medical College, Vellore, India
⨯
Biju George,

Affiliation Department of Haematology, Christian Medical College, Vellore, India
⨯
Poonkuzhali Balasubramanian,

Affiliation Department of Haematology, Christian Medical College, Vellore, India
⨯
[ ... ],
Vikram Mathews

* E-mail: vikram@cmcvellore.ac.in

Affiliation Department of Haematology, Christian Medical College, Vellore, India
⨯
[ view all ]
[ view less ]

Comparison of Newly Diagnosed and Relapsed Patients with Acute Promyelocytic Leukemia Treated with Arsenic Trioxide: Insight into Mechanisms of Resistance

Ezhilarasi Chendamarai,
Saravanan Ganesan,
Ansu Abu Alex,
Vandana Kamath,
Sukesh C. Nair,
Arun Jose Nellickal,
Nancy Beryl Janet,
Vivi Srivastava,
Kavitha M. Lakshmi,
Auro Viswabandya

Published: March 30, 2015
https://doi.org/10.1371/journal.pone.0121912

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Gene regulation
Is the Subject Area "Gene regulation" applicable to this article?

Thanks for your feedback.
Microarrays
Is the Subject Area "Microarrays" applicable to this article?

Thanks for your feedback.
Gene expression
Is the Subject Area "Gene expression" applicable to this article?

Thanks for your feedback.
Cancer detection and diagnosis
Is the Subject Area "Cancer detection and diagnosis" applicable to this article?

Thanks for your feedback.
Stromal cells
Is the Subject Area "Stromal cells" applicable to this article?

Thanks for your feedback.
Cancer treatment
Is the Subject Area "Cancer treatment" applicable to this article?

Thanks for your feedback.
Leukemia
Is the Subject Area "Leukemia" applicable to this article?

Thanks for your feedback.
Arsenic
Is the Subject Area "Arsenic" applicable to this article?

Thanks for your feedback.