Extended RAS and BRAF Mutation Analysis Using Next-Generation Sequencing

Kazuko Sakai; Junji Tsurutani; Takeharu Yamanaka; Azusa Yoneshige; Akihiko Ito; Yosuke Togashi; Marco A. De Velasco; Masato Terashima; Yoshihiko Fujita; Shuta Tomida; Takao Tamura; Kazuhiko Nakagawa; Kazuto Nishio

doi:10.1371/journal.pone.0121891

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Open Access

Peer-reviewed

Research Article

Extended RAS and BRAF Mutation Analysis Using Next-Generation Sequencing

Kazuko Sakai,

Affiliation Department of Genome Biology, Kinki University Faculty of Medicine, Osaka-Sayama, Osaka, Japan
⨯
Junji Tsurutani,

Affiliation Department of Medical Oncology, Kinki University Faculty of Medicine, Osaka-Sayama, Osaka, Japan
⨯
Takeharu Yamanaka,

Affiliation Department of Biostatistics, Yokohama City University, Yokohama, Kanagawa, Japan
⨯
Azusa Yoneshige,

Affiliation Department of Pathology, Kinki University Faculty of Medicine, Osaka-Sayama, Osaka, Japan
⨯
Akihiko Ito,

Affiliation Department of Pathology, Kinki University Faculty of Medicine, Osaka-Sayama, Osaka, Japan
⨯
Yosuke Togashi,

Affiliation Department of Genome Biology, Kinki University Faculty of Medicine, Osaka-Sayama, Osaka, Japan
⨯
Marco A. De Velasco,

Affiliation Department of Genome Biology, Kinki University Faculty of Medicine, Osaka-Sayama, Osaka, Japan
⨯
Masato Terashima,

Affiliation Department of Genome Biology, Kinki University Faculty of Medicine, Osaka-Sayama, Osaka, Japan
⨯
Yoshihiko Fujita,

Affiliation Department of Genome Biology, Kinki University Faculty of Medicine, Osaka-Sayama, Osaka, Japan
⨯
Shuta Tomida,

Affiliation Department of Genome Biology, Kinki University Faculty of Medicine, Osaka-Sayama, Osaka, Japan
⨯
Takao Tamura,

Affiliation Department of Medical Oncology, Kinki University Faculty of Medicine, Osaka-Sayama, Osaka, Japan
⨯
Kazuhiko Nakagawa,

Affiliation Department of Medical Oncology, Kinki University Faculty of Medicine, Osaka-Sayama, Osaka, Japan
⨯
Kazuto Nishio

* E-mail: knishio@med.kindai.ac.jp

Affiliation Department of Genome Biology, Kinki University Faculty of Medicine, Osaka-Sayama, Osaka, Japan
⨯

Extended RAS and BRAF Mutation Analysis Using Next-Generation Sequencing

Kazuko Sakai,
Junji Tsurutani,
Takeharu Yamanaka,
Azusa Yoneshige,
Akihiko Ito,
Yosuke Togashi,
Marco A. De Velasco,
Masato Terashima,
Yoshihiko Fujita,
Shuta Tomida

Published: May 8, 2015
https://doi.org/10.1371/journal.pone.0121891

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Mutation detection
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Polymerase chain reaction
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Colorectal cancer
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Cancer treatment
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Mutational analysis
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Next-generation sequencing
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Nucleotides
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