Identification of Small Molecules that Disrupt Signaling between ABL and Its Positive Regulator RIN1

• Pamela Y. Ting,

  Affiliation Molecular Biology Institute, Jonsson Comprehensive Cancer Center, Department of Biological Chemistry, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America

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• Robert Damoiseaux,

  Affiliation California NanoSystems Institute, University of California Los Angeles, Los Angeles, California, United States of America

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• Björn Titz,

  Affiliation Department of Molecular and Medical Pharmacology, Crump Institute for Molecular Imaging, University of California at Los Angeles Metabolomics and Proteomics Center, California NanoSystems Institute and Jonsson Comprehensive Cancer Center, University of California Los Angeles, Los Angeles, California, United States of America

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• Kenneth A. Bradley,

  Affiliation Department of Microbiology, Immunology and Molecular Genetics, Jonsson Comprehensive Cancer Center, and California NanoSystems Institute, University of California Los Angeles, Los Angeles, California, United States of America

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• Thomas G. Graeber,

  Affiliation Department of Molecular and Medical Pharmacology, Crump Institute for Molecular Imaging, University of California at Los Angeles Metabolomics and Proteomics Center, California NanoSystems Institute and Jonsson Comprehensive Cancer Center, University of California Los Angeles, Los Angeles, California, United States of America

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• Virneliz Fernández-Vega,

  Affiliation The Scripps Research Institute-FL, Lead Identification, Translational Research Institute, Jupiter, Florida, United States of America

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• Thomas D. Bannister,

  Affiliation The Scripps Research Institute-FL, Department of Chemistry, Translational Research Institute, Jupiter, Florida, United States of America

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• Peter Chase,

  Affiliation The Scripps Research Institute-FL, Lead Identification, Translational Research Institute, Jupiter, Florida, United States of America

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• Reji Nair,

  Affiliation The Scripps Research Institute-FL, Department of Chemistry, Translational Research Institute, Jupiter, Florida, United States of America

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• Louis Scampavia,

  Affiliation The Scripps Research Institute-FL, Lead Identification, Translational Research Institute, Jupiter, Florida, United States of America

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• Peter Hodder,

  Current address: Amgen, Inc., Thousand Oaks, California, United States of America

  Affiliation The Scripps Research Institute-FL, Lead Identification, Translational Research Institute, Jupiter, Florida, United States of America

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• Timothy P. Spicer,

  Affiliation The Scripps Research Institute-FL, Lead Identification, Translational Research Institute, Jupiter, Florida, United States of America

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• John Colicelli

  * E-mail: colicelli@mednet.ucla.edu

  Affiliation Molecular Biology Institute, Jonsson Comprehensive Cancer Center, Department of Biological Chemistry, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America

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