Impairment of Type I but Not Type III IFN Signaling by Hepatitis C Virus Infection Influences Antiviral Responses in Primary Human Hepatocytes

Open Access

Peer-reviewed

Research Article

Jacques Friborg ,

* E-mail: jacques.friborg@bms.com

Affiliation Discovery Virology, Bristol-Myers Squibb Research and Development, Wallingford, Connecticut, United States of America, 06492
⨯
Petra Ross-Macdonald,

Affiliation Applied Genomics, Bristol-Myers Squibb Research and Development, Hopewell, NJ, United States of America
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Jian Cao,

Affiliation Applied Genomics, Bristol-Myers Squibb Research and Development, Hopewell, NJ, United States of America
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Ryan Willard,

Affiliation Discovery Virology, Bristol-Myers Squibb Research and Development, Wallingford, Connecticut, United States of America, 06492
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Baiqing Lin,

Affiliation Discovery Virology, Bristol-Myers Squibb Research and Development, Wallingford, Connecticut, United States of America, 06492
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Betsy Eggers,

Affiliation Discovery Virology, Bristol-Myers Squibb Research and Development, Wallingford, Connecticut, United States of America, 06492
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Fiona McPhee

Affiliation Discovery Virology, Bristol-Myers Squibb Research and Development, Wallingford, Connecticut, United States of America, 06492
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Hepatocytes
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Hepatitis C virus
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Interferons
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Phosphorylation
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STAT signaling
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Viral replication
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Immunostaining
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JAK-STAT signaling cascade
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