Host APOBEC3G Protein Inhibits HCV Replication through Direct Binding at NS3

Yan-Ping Zhu; Zong-Gen Peng; Zhou-Yi Wu; Jian-Rui Li; Meng-Hao Huang; Shu-Yi Si; Jian-Dong Jiang

doi:10.1371/journal.pone.0121608

Loading metrics

Open Access

Peer-reviewed

Research Article

Host APOBEC3G Protein Inhibits HCV Replication through Direct Binding at NS3

Yan-Ping Zhu ,

Contributed equally to this work with: Yan-Ping Zhu, Zong-Gen Peng

Affiliation Laboratory of Antiviral Research, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences/Peking Union Medical College, Beijing, 100050, China
⨯
Zong-Gen Peng ,

Contributed equally to this work with: Yan-Ping Zhu, Zong-Gen Peng

* E-mail: pumcpzg@126.com (ZGP); jiang.jdong@163.com (JDJ)

Affiliation Laboratory of Antiviral Research, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences/Peking Union Medical College, Beijing, 100050, China
⨯
Zhou-Yi Wu,

Affiliation Laboratory of Antiviral Research, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences/Peking Union Medical College, Beijing, 100050, China
⨯
Jian-Rui Li,

Affiliation Laboratory of Antiviral Research, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences/Peking Union Medical College, Beijing, 100050, China
⨯
Meng-Hao Huang,

Affiliation Laboratory of Antiviral Research, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences/Peking Union Medical College, Beijing, 100050, China
⨯
Shu-Yi Si,

Affiliation Laboratory of Antiviral Research, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences/Peking Union Medical College, Beijing, 100050, China
⨯
Jian-Dong Jiang

* E-mail: pumcpzg@126.com (ZGP); jiang.jdong@163.com (JDJ)

Affiliations Laboratory of Antiviral Research, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences/Peking Union Medical College, Beijing, 100050, China, State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences/Peking Union Medical College, Beijing, 100050, China
⨯

Host APOBEC3G Protein Inhibits HCV Replication through Direct Binding at NS3

Yan-Ping Zhu,
Zong-Gen Peng,
Zhou-Yi Wu,
Jian-Rui Li,
Meng-Hao Huang,
Shu-Yi Si,
Jian-Dong Jiang

Published: March 26, 2015
https://doi.org/10.1371/journal.pone.0121608

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Hepatitis C virus
Is the Subject Area "Hepatitis C virus" applicable to this article?

Thanks for your feedback.
Transfection
Is the Subject Area "Transfection" applicable to this article?

Thanks for your feedback.
Helicases
Is the Subject Area "Helicases" applicable to this article?

Thanks for your feedback.
Immunoprecipitation
Is the Subject Area "Immunoprecipitation" applicable to this article?

Thanks for your feedback.
Small interfering RNA
Is the Subject Area "Small interfering RNA" applicable to this article?

Thanks for your feedback.
Plasmid construction
Is the Subject Area "Plasmid construction" applicable to this article?

Thanks for your feedback.
Protein interactions
Is the Subject Area "Protein interactions" applicable to this article?

Thanks for your feedback.
Viral replication
Is the Subject Area "Viral replication" applicable to this article?

Thanks for your feedback.