Eicosapentaenoic Acid Ameliorates Non-Alcoholic Steatohepatitis in a Novel Mouse Model Using Melanocortin 4 Receptor-Deficient Mice

• Kuniha Konuma ,

  Contributed equally to this work with: Kuniha Konuma, Michiko Itoh

  Affiliations Department of Molecular Endocrinology and Metabolism, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan, Department of Periodontology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan

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• Michiko Itoh ,

  Contributed equally to this work with: Kuniha Konuma, Michiko Itoh

  Affiliation Department of Molecular Endocrinology and Metabolism, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan

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• Takayoshi Suganami ,

  * E-mail: suganami.mem@tmd.ac.jp

  Affiliations Department of Organ Network and Metabolism, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan, Japan Science and Technology Agency, PRESTO, Tokyo, Japan

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• Sayaka Kanai,

  Affiliation Department of Molecular Endocrinology and Metabolism, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan

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• Nobutaka Nakagawa,

  Affiliation Department of Molecular Endocrinology and Metabolism, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan

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• Takeru Sakai,

  Affiliation Department of Molecular Endocrinology and Metabolism, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan

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• Hiroyuki Kawano,

  Affiliation Development Research, Pharmaceutical Research Center, Mochida Pharmaceutical, Shizuoka, Japan

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• Mitsuko Hara,

  Affiliation Micro-Signaling Regulation Technology Unit, RIKEN Center for Life Science Technologies, Wako, Japan

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• Soichi Kojima,

  Affiliation Micro-Signaling Regulation Technology Unit, RIKEN Center for Life Science Technologies, Wako, Japan

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• Yuichi Izumi,

  Affiliation Department of Periodontology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan

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• Yoshihiro Ogawa

  Affiliations Department of Molecular Endocrinology and Metabolism, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan, Japan Science and Technology Agency, CREST, Tokyo, Japan

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