Renal Intercalated Cells Sense and Mediate Inflammation via the P2Y14 Receptor

Anie Azroyan; Virna Cortez-Retamozo; Richard Bouley; Rachel Liberman; Ye Chun Ruan; Evgeny Kiselev; Kenneth A. Jacobson; Mikael J. Pittet; Dennis Brown; Sylvie Breton

doi:10.1371/journal.pone.0121419

Loading metrics

Open Access

Peer-reviewed

Research Article

Renal Intercalated Cells Sense and Mediate Inflammation via the P2Y₁₄ Receptor

Anie Azroyan,

Affiliations Center for Systems Biology, Massachusetts General Hospital/Harvard Medical School, Boston, Massachusetts, United States of America, Program in Membrane Biology/Nephrology Division, Massachusetts General Hospital/Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Virna Cortez-Retamozo,

Affiliation Center for Systems Biology, Massachusetts General Hospital/Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Richard Bouley,

Affiliations Center for Systems Biology, Massachusetts General Hospital/Harvard Medical School, Boston, Massachusetts, United States of America, Program in Membrane Biology/Nephrology Division, Massachusetts General Hospital/Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Rachel Liberman,

Affiliations Center for Systems Biology, Massachusetts General Hospital/Harvard Medical School, Boston, Massachusetts, United States of America, Program in Membrane Biology/Nephrology Division, Massachusetts General Hospital/Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Ye Chun Ruan,

Affiliations Center for Systems Biology, Massachusetts General Hospital/Harvard Medical School, Boston, Massachusetts, United States of America, Program in Membrane Biology/Nephrology Division, Massachusetts General Hospital/Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Evgeny Kiselev,

Affiliation Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Kenneth A. Jacobson,

Affiliation Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Mikael J. Pittet,

Affiliation Center for Systems Biology, Massachusetts General Hospital/Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Dennis Brown,

Affiliations Center for Systems Biology, Massachusetts General Hospital/Harvard Medical School, Boston, Massachusetts, United States of America, Program in Membrane Biology/Nephrology Division, Massachusetts General Hospital/Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Sylvie Breton

* E-mail: Breton.Sylvie@MGH.Harvard.edu

Affiliations Center for Systems Biology, Massachusetts General Hospital/Harvard Medical School, Boston, Massachusetts, United States of America, Program in Membrane Biology/Nephrology Division, Massachusetts General Hospital/Harvard Medical School, Boston, Massachusetts, United States of America
⨯

Renal Intercalated Cells Sense and Mediate Inflammation via the P2Y₁₄ Receptor

Anie Azroyan,
Virna Cortez-Retamozo,
Richard Bouley,
Rachel Liberman,
Ye Chun Ruan,
Evgeny Kiselev,
Kenneth A. Jacobson,
Mikael J. Pittet,
Dennis Brown,
Sylvie Breton

Published: March 23, 2015
https://doi.org/10.1371/journal.pone.0121419

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Kidneys
Is the Subject Area "Kidneys" applicable to this article?

Thanks for your feedback.
Neutrophils
Is the Subject Area "Neutrophils" applicable to this article?

Thanks for your feedback.
Inflammation
Is the Subject Area "Inflammation" applicable to this article?

Thanks for your feedback.
Cell membranes
Is the Subject Area "Cell membranes" applicable to this article?

Thanks for your feedback.
Cloning
Is the Subject Area "Cloning" applicable to this article?

Thanks for your feedback.
Membrane proteins
Is the Subject Area "Membrane proteins" applicable to this article?

Thanks for your feedback.
Immune cells
Is the Subject Area "Immune cells" applicable to this article?

Thanks for your feedback.
Chemokines
Is the Subject Area "Chemokines" applicable to this article?

Thanks for your feedback.