Suppression of TGF-β1/Smad Signaling Pathway by Sesamin Contributes to the Attenuation of Myocardial Fibrosis in Spontaneously Hypertensive Rats

Open Access

Peer-reviewed

Research Article

Suppression of TGF-β₁/Smad Signaling Pathway by Sesamin Contributes to the Attenuation of Myocardial Fibrosis in Spontaneously Hypertensive Rats

Mengqiu Zhao,

Affiliation Department of Pharmacology, Wannan Medical College, Wuhu, 241002, China
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Shuguo Zheng ,

* E-mail: zhengsg2000@163.com (SGZ); anhuiwuyuanjie@126.com (YJW)

Affiliation Department of Pharmacology, Wannan Medical College, Wuhu, 241002, China
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Jieren Yang,

Affiliation Department of Pharmacology, Wannan Medical College, Wuhu, 241002, China
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Yuanjie Wu ,

* E-mail: zhengsg2000@163.com (SGZ); anhuiwuyuanjie@126.com (YJW)

Affiliation Department of Basic Theory of Chinese Medicine, Anhui University of Chinese Medicine, Hefei, 230038, China
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Younan Ren,

Affiliation Department of Pharmacology, Wannan Medical College, Wuhu, 241002, China
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Xiang Kong,

Affiliation Department of Pharmacology, Wannan Medical College, Wuhu, 241002, China
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Wei Li,

Affiliation Department of Pharmacology, Wannan Medical College, Wuhu, 241002, China
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Jiali Xuan

Affiliation Department of Pharmacology, Wannan Medical College, Wuhu, 241002, China
⨯

Collagens
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Fibrosis
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Hypertension
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Fibroblasts
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Antioxidants
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Phosphorylation
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Protein expression
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Blood pressure
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