MTHFR 677C>T Polymorphism Increases the Male Infertility Risk: A Meta-Analysis Involving 26 Studies

Mancheng Gong; Wenjing Dong; Tingyu He; Zhirong Shi; Guiying Huang; Rui Ren; Sichong Huang; Shaopeng Qiu; Runqiang Yuan

doi:10.1371/journal.pone.0121147

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Peer-reviewed

Research Article

MTHFR 677C>T Polymorphism Increases the Male Infertility Risk: A Meta-Analysis Involving 26 Studies

Mancheng Gong,

Affiliations Department of Urology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, 510080, China, Department of Andrology, Zhongshan Affiliated Hospital of Sun Yat-sen University, Zhongshan, Guangdong, 528403, China
⨯
Wenjing Dong,

Affiliation Department of Oncology, Zhongshan Affiliated Hospital of Sun Yat-sen University, Zhongshan, Guangdong, 528403, China
⨯
Tingyu He,

Affiliation Department of Reproductive Center, Zhongshan Affiliated Hospital of Sun Yat-sen University, Zhongshan, Guangdong, 528403, China
⨯
Zhirong Shi,

Affiliation Department of Pharmacy, The Second People’s Hospital of Zhuhai, Zhuhai, Guangdong, 519020, China
⨯
Guiying Huang,

Affiliation The Second General Department, Zhongshan Affiliated Hospital of Sun Yat-sen University, Zhongshan, Guangdong, 528403, China
⨯
Rui Ren,

Affiliation Department of Andrology, Zhongshan Affiliated Hospital of Sun Yat-sen University, Zhongshan, Guangdong, 528403, China
⨯
Sichong Huang,

Affiliation Department of Andrology, Zhongshan Affiliated Hospital of Sun Yat-sen University, Zhongshan, Guangdong, 528403, China
⨯
Shaopeng Qiu ,

* E-mail: medicinegd@163.com (SPQ); yuanrunqiang2013@163.com (RQY)

Affiliation Department of Urology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, 510080, China
⨯
Runqiang Yuan

* E-mail: medicinegd@163.com (SPQ); yuanrunqiang2013@163.com (RQY)

Affiliation Department of Andrology, Zhongshan Affiliated Hospital of Sun Yat-sen University, Zhongshan, Guangdong, 528403, China
⨯

MTHFR 677C>T Polymorphism Increases the Male Infertility Risk: A Meta-Analysis Involving 26 Studies

Mancheng Gong,
Wenjing Dong,
Tingyu He,
Zhirong Shi,
Guiying Huang,
Rui Ren,
Sichong Huang,
Shaopeng Qiu,
Runqiang Yuan

Published: March 20, 2015
https://doi.org/10.1371/journal.pone.0121147

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