Both Ubiquitin Ligases FBXW8 and PARK2 Are Sequestrated into Insolubility by ATXN2 PolyQ Expansions, but Only FBXW8 Expression Is Dysregulated

• Melanie Vanessa Halbach,

  Affiliation Experimental Neurology, Dept. of Neurology, Goethe University Medical School, Theodor Stern Kai 7, 60590 Frankfurt am Main, Germany

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• Tanja Stehning,

  Affiliation Experimental Neurology, Dept. of Neurology, Goethe University Medical School, Theodor Stern Kai 7, 60590 Frankfurt am Main, Germany

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• Ewa Damrath,

  Affiliation Experimental Neurology, Dept. of Neurology, Goethe University Medical School, Theodor Stern Kai 7, 60590 Frankfurt am Main, Germany

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• Marina Jendrach,

  Affiliation Experimental Neurology, Dept. of Neurology, Goethe University Medical School, Theodor Stern Kai 7, 60590 Frankfurt am Main, Germany

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• Nesli Ece Şen,

  Affiliation Neurodegeneration Research Laboratory (NDAL), Molecular Biology and Genetics Department, Boğaziçi University, 34470 Istanbul, Turkey

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• A. Nazlı Başak,

  Affiliation Neurodegeneration Research Laboratory (NDAL), Molecular Biology and Genetics Department, Boğaziçi University, 34470 Istanbul, Turkey

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• Georg Auburger

  * E-mail: auburger@em.uni-frankfurt.de

  Affiliation Experimental Neurology, Dept. of Neurology, Goethe University Medical School, Theodor Stern Kai 7, 60590 Frankfurt am Main, Germany

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