Genomic Characterization of Burkholderia pseudomallei Isolates Selected for Medical Countermeasures Testing: Comparative Genomics Associated with Differential Virulence

Jason W. Sahl; Christopher J. Allender; Rebecca E. Colman; Katy J. Califf; James M. Schupp; Bart J. Currie; Kristopher E. Van Zandt; H. Carl Gelhaus; Paul Keim; Apichai Tuanyok

doi:10.1371/journal.pone.0121052

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Peer-reviewed

Research Article

Genomic Characterization of Burkholderia pseudomallei Isolates Selected for Medical Countermeasures Testing: Comparative Genomics Associated with Differential Virulence

Jason W. Sahl ,

* E-mail: jasonsahl@gmail.com

Affiliations Department of Pathogen Genomics, Translational Genomics Research Institute, Flagstaff, Arizona, United States of America, Center for Microbial Genetics and Genomics, Northern Arizona University, Flagstaff, Arizona, United States of America
⨯
Christopher J. Allender,

Affiliation Center for Microbial Genetics and Genomics, Northern Arizona University, Flagstaff, Arizona, United States of America
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Rebecca E. Colman,

Affiliation Department of Pathogen Genomics, Translational Genomics Research Institute, Flagstaff, Arizona, United States of America
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Katy J. Califf,

Affiliation Center for Microbial Genetics and Genomics, Northern Arizona University, Flagstaff, Arizona, United States of America
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James M. Schupp,

Affiliation Department of Pathogen Genomics, Translational Genomics Research Institute, Flagstaff, Arizona, United States of America
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Bart J. Currie,

Affiliation Department of Tropical and Emerging Infectious Diseases, Menzies School of Health Research, Casuarina NT, Australia
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Kristopher E. Van Zandt,

Affiliation Battelle Biomedical Research Center (BBRC), Columbus, Ohio, United States of America
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H. Carl Gelhaus,

Affiliation Battelle Biomedical Research Center (BBRC), Columbus, Ohio, United States of America
⨯
Paul Keim,

Affiliations Department of Pathogen Genomics, Translational Genomics Research Institute, Flagstaff, Arizona, United States of America, Center for Microbial Genetics and Genomics, Northern Arizona University, Flagstaff, Arizona, United States of America
⨯
Apichai Tuanyok

Affiliation Department of Tropical Medicine, Medical Microbiology and Pharmacology, and Pacific Center for Emerging Infections Diseases Research, University of Hawaii at Manoa, Honolulu, Hawaii, United States of America
⨯

Genomic Characterization of Burkholderia pseudomallei Isolates Selected for Medical Countermeasures Testing: Comparative Genomics Associated with Differential Virulence

Jason W. Sahl,
Christopher J. Allender,
Rebecca E. Colman,
Katy J. Califf,
James M. Schupp,
Bart J. Currie,
Kristopher E. Van Zandt,
H. Carl Gelhaus,
Paul Keim,
Apichai Tuanyok

Published: March 24, 2015
https://doi.org/10.1371/journal.pone.0121052

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