Discovery and Cardioprotective Effects of the First Non-Peptide Agonists of the G Protein-Coupled Prokineticin Receptor-1

• Adeline Gasser ,

  Contributed equally to this work with: Adeline Gasser, Simone Brogi

  Affiliation Biotechnology and Cell Signaling Laboratory (UMR 7242), CNRS-University of Strasbourg, Illkirch, France

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• Simone Brogi ,

  Contributed equally to this work with: Adeline Gasser, Simone Brogi

  Affiliations European Research Centre for Drug Discovery and Development (NatSynDrugs), University of Siena, Siena, Italy, Departments of Biotechnology, Chemistry and Pharmacy, University of Siena, Siena, Italy

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• Kyoji Urayama,

  Affiliation Biotechnology and Cell Signaling Laboratory (UMR 7242), CNRS-University of Strasbourg, Illkirch, France

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• Toshishide Nishi,

  Affiliations Biotechnology and Cell Signaling Laboratory (UMR 7242), CNRS-University of Strasbourg, Illkirch, France, Department of Pharmacology and Toxicology, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, 812–8582, Japan

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• Hitoshi Kurose,

  Affiliation Department of Pharmacology and Toxicology, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, 812–8582, Japan

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• Andrea Tafi,

  Affiliation Departments of Biotechnology, Chemistry and Pharmacy, University of Siena, Siena, Italy

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• Nigel Ribeiro,

  Affiliation Therapeutic Innovation Laboratory (UMR7200), CNRS-University of Strasbourg, Illkirch, France

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• Laurent Désaubry ,

  * E-mail: desaubry@unistra.fr (LD); nebigil@unistra.fr (CGN)

  Affiliation Therapeutic Innovation Laboratory (UMR7200), CNRS-University of Strasbourg, Illkirch, France

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• Canan G. Nebigil

  * E-mail: desaubry@unistra.fr (LD); nebigil@unistra.fr (CGN)

  Affiliation Biotechnology and Cell Signaling Laboratory (UMR 7242), CNRS-University of Strasbourg, Illkirch, France

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