miR-29a/b Enhances Cell Migration and Invasion in Nasopharyngeal Carcinoma Progression by Regulating SPARC and COL3A1 Gene Expression

Feifei Qiu; Rui Sun; Ning Deng; Tianyu Guo; Yange Cao; Ying Yu; Xuejun Wang; Bingcheng Zou; Songmei Zhang; Tao Jing; Tao Ling; Jun Xie; Qing Zhang

doi:10.1371/journal.pone.0120969

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Open Access

Peer-reviewed

Research Article

miR-29a/b Enhances Cell Migration and Invasion in Nasopharyngeal Carcinoma Progression by Regulating SPARC and COL3A1 Gene Expression

Feifei Qiu ,

Contributed equally to this work with: Feifei Qiu, Rui Sun

Affiliation State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, China
⨯
Rui Sun ,

Contributed equally to this work with: Feifei Qiu, Rui Sun

Affiliation State Key Laboratory of Oncology in Southern China; Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, China
⨯
Ning Deng,

Affiliation Key Laboratory of Molecular Immunology and Antibody Engineering of Guangdong Province, Antibody Engineering Center in Jinan University, Guangzhou, China
⨯
Tianyu Guo,

Affiliation State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, China
⨯
Yange Cao,

Affiliation State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, China
⨯
Ying Yu,

Affiliation State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, China
⨯
Xuejun Wang,

Affiliation State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, China
⨯
Bingcheng Zou,

Affiliation State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, China
⨯
Songmei Zhang,

Affiliation State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, China
⨯
Tao Jing,

Affiliation State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, China
⨯
Tao Ling,

Affiliation State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, China
⨯
Jun Xie ,

* E-mail: lsszq@mail.sysu.edu.cn (QZ); xiejunhy@yahoo.com.cn (JX)

Affiliation Key Laboratory of Tropical & Subtropical Fishery Resource Application & Cultivation, Ministry of Agriculture, Pearl River Fisheries Research Institute of CAFS, Guangzhou, Guangdong, China
⨯
Qing Zhang

* E-mail: lsszq@mail.sysu.edu.cn (QZ); xiejunhy@yahoo.com.cn (JX)

Affiliation State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-sen University, Guangzhou, China
⨯

miR-29a/b Enhances Cell Migration and Invasion in Nasopharyngeal Carcinoma Progression by Regulating SPARC and COL3A1 Gene Expression

Feifei Qiu,
Rui Sun,
Ning Deng,
Tianyu Guo,
Yange Cao,
Ying Yu,
Xuejun Wang,
Bingcheng Zou,
Songmei Zhang,
Tao Jing

Published: March 18, 2015
https://doi.org/10.1371/journal.pone.0120969

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Nasopharyngeal carcinoma
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MicroRNAs
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Metastasis
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Gene expression
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Cell migration
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Extracellular matrix proteins
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Lung and intrathoracic tumors
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