Urinary Biomarkers TIMP-2 and IGFBP7 Early Predict Acute Kidney Injury after Major Surgery

Ivan Gocze; Matthias Koch; Philipp Renner; Florian Zeman; Bernhard M. Graf; Marc H. Dahlke; Michael Nerlich; Hans J. Schlitt; John A. Kellum; Thomas Bein

doi:10.1371/journal.pone.0120863

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Open Access

Peer-reviewed

Research Article

Urinary Biomarkers TIMP-2 and IGFBP7 Early Predict Acute Kidney Injury after Major Surgery

Ivan Gocze ,

* E-mail: ivan.goecze@ukr.de

Affiliation Department of Surgery, University Medical Center Regensburg, Franz-Josef-Strauss-Allee 11, 93053 Regensburg, Germany
⨯
Matthias Koch,

Affiliation Department of Trauma Surgery, University Medical Center Regensburg, Franz-Josef-Strauss-Allee 11, 93053 Regensburg, Germany
⨯
Philipp Renner,

Affiliation Department of Surgery, University Medical Center Regensburg, Franz-Josef-Strauss-Allee 11, 93053 Regensburg, Germany
⨯
Florian Zeman,

Affiliation Center for Clinical Studies, University Medical Center Regensburg, Franz-Josef-Strauss-Allee 11, 93053 Regensburg, Germany
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Bernhard M. Graf,

Affiliation Department of Anesthesiology, University Medical Center Regensburg, Franz-Josef- Strauss-Allee 11, 93053 Regensburg, Germany
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Marc H. Dahlke,

Affiliation Department of Surgery, University Medical Center Regensburg, Franz-Josef-Strauss-Allee 11, 93053 Regensburg, Germany
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Michael Nerlich,

Affiliation Department of Trauma Surgery, University Medical Center Regensburg, Franz-Josef-Strauss-Allee 11, 93053 Regensburg, Germany
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Hans J. Schlitt,

Affiliation Department of Surgery, University Medical Center Regensburg, Franz-Josef-Strauss-Allee 11, 93053 Regensburg, Germany
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John A. Kellum,

Affiliation Center for Critical Care Nephrology and CRISMA (Clinical Research, Investigation, and Systems Modeling of Acute Illness) Center, Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA 15621, United States of America
⨯
Thomas Bein

Affiliations Department of Surgery, University Medical Center Regensburg, Franz-Josef-Strauss-Allee 11, 93053 Regensburg, Germany, Center for Clinical Studies, University Medical Center Regensburg, Franz-Josef-Strauss-Allee 11, 93053 Regensburg, Germany
⨯

Urinary Biomarkers TIMP-2 and IGFBP7 Early Predict Acute Kidney Injury after Major Surgery

Ivan Gocze,
Matthias Koch,
Philipp Renner,
Florian Zeman,
Bernhard M. Graf,
Marc H. Dahlke,
Michael Nerlich,
Hans J. Schlitt,
John A. Kellum,
Thomas Bein

Published: March 23, 2015
https://doi.org/10.1371/journal.pone.0120863

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