Smad4 Loss Synergizes with TGFα Overexpression in Promoting Pancreatic Metaplasia, PanIN Development, and Fibrosis

• Dario Garcia-Carracedo,

  Affiliations The Department of Pathology, Columbia University Medical Center, New York, New York, United States of America, Herbert Irving Comprehensive Cancer Center, Columbia University Medical Center, New York, New York, United States of America

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• Chih-Chieh Yu,

  Affiliations The Department of Pathology, Columbia University Medical Center, New York, New York, United States of America, Herbert Irving Comprehensive Cancer Center, Columbia University Medical Center, New York, New York, United States of America

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• Nathan Akhavan,

  Affiliation Herbert Irving Comprehensive Cancer Center, Columbia University Medical Center, New York, New York, United States of America

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• Stuart A. Fine,

  Affiliation Herbert Irving Comprehensive Cancer Center, Columbia University Medical Center, New York, New York, United States of America

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• Frank Schönleben,

  Affiliation The Department of Vascular Surgery in the Hospital of the University of Munich, Grosshadern, Germany

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• Naoki Maehara,

  Affiliation Department of Surgical Oncology and Regulation of Organ Function, Miyazaki University School of Medicine, Miyazaki, Japan

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• Dillon C. Karg,

  Affiliation Herbert Irving Comprehensive Cancer Center, Columbia University Medical Center, New York, New York, United States of America

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• Chuangao Xie,

  Affiliations The Department of Pathology, Columbia University Medical Center, New York, New York, United States of America, Herbert Irving Comprehensive Cancer Center, Columbia University Medical Center, New York, New York, United States of America

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• Wanglong Qiu,

  Affiliations The Department of Pathology, Columbia University Medical Center, New York, New York, United States of America, Herbert Irving Comprehensive Cancer Center, Columbia University Medical Center, New York, New York, United States of America

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• Robert L. Fine,

  Affiliations Department of Medicine, Columbia University Medical Center, New York, New York, United States of America, Pancreas Center, Columbia University Medical Center, New York, New York, United States of America

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• Helen E. Remotti,

  Affiliations The Department of Pathology, Columbia University Medical Center, New York, New York, United States of America, Department of Surgical Oncology and Regulation of Organ Function, Miyazaki University School of Medicine, Miyazaki, Japan

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• Gloria H. Su

  * E-mail: gs2157@columbia.edu

  Affiliations The Department of Pathology, Columbia University Medical Center, New York, New York, United States of America, Herbert Irving Comprehensive Cancer Center, Columbia University Medical Center, New York, New York, United States of America, Pancreas Center, Columbia University Medical Center, New York, New York, United States of America, Department of Otolaryngology and Head and Neck Surgery, Columbia University Medical Center, New York, New York, United States of America

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