Quinidine, but Not Eicosanoid Antagonists or Dexamethasone, Protect the Gut from Platelet Activating Factor-Induced Vasoconstriction, Edema and Paralysis

Ingmar Lautenschläger; Inéz Frerichs; Heike Dombrowsky; Jürgen Sarau; Torsten Goldmann; Karina Zitta; Martin Albrecht; Norbert Weiler; Stefan Uhlig

doi:10.1371/journal.pone.0120802

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Open Access

Peer-reviewed

Research Article

Quinidine, but Not Eicosanoid Antagonists or Dexamethasone, Protect the Gut from Platelet Activating Factor-Induced Vasoconstriction, Edema and Paralysis

Ingmar Lautenschläger ,

* E-mail: ingmar.lautenschlaeger@uksh.de

Affiliations Department of Anesthesiology and Intensive Care Medicine, University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, Germany, Division of Barrier Integrity, Research Center Borstel, Leibniz-Center for Medicine and Biosciences, Borstel, Germany
⨯
Inéz Frerichs,

Affiliation Department of Anesthesiology and Intensive Care Medicine, University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, Germany
⨯
Heike Dombrowsky,

Affiliation Division of Barrier Integrity, Research Center Borstel, Leibniz-Center for Medicine and Biosciences, Borstel, Germany
⨯
Jürgen Sarau,

Affiliations Division of Barrier Integrity, Research Center Borstel, Leibniz-Center for Medicine and Biosciences, Borstel, Germany, Division of Mucosal Immunology and Diagnostic, Research Center Borstel, Leibniz-Center for Medicine and Biosciences, Borstel, Germany
⨯
Torsten Goldmann,

Affiliation Division of Clinical and Experimental Pathology, Research Center Borstel, Leibniz-Center for Medicine and Biosciences, Borstel, Germany
⨯
Karina Zitta,

Affiliation Department of Anesthesiology and Intensive Care Medicine, University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, Germany
⨯
Martin Albrecht,

Affiliation Department of Anesthesiology and Intensive Care Medicine, University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, Germany
⨯
Norbert Weiler,

Affiliation Department of Anesthesiology and Intensive Care Medicine, University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, Germany
⨯
Stefan Uhlig

Affiliation Institute of Pharmacology and Toxicology, Medical Faculty, RWTH Aachen University, Aachen, Germany
⨯

Quinidine, but Not Eicosanoid Antagonists or Dexamethasone, Protect the Gut from Platelet Activating Factor-Induced Vasoconstriction, Edema and Paralysis

Ingmar Lautenschläger,
Inéz Frerichs,
Heike Dombrowsky,
Jürgen Sarau,
Torsten Goldmann,
Karina Zitta,
Martin Albrecht,
Norbert Weiler,
Stefan Uhlig

Published: March 20, 2015
https://doi.org/10.1371/journal.pone.0120802

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