Knockdown of CDK2AP1 in Primary Human Fibroblasts Induces p53 Dependent Senescence

Open Access

Peer-reviewed

Research Article

Khaled N. Alsayegh,

Affiliations Department of Human and Molecular Genetics, Virginia Commonwealth University, Richmond, United States of America, King Abdullah International Medical Research Center, King Saud bin Abdulaziz University for Health Sciences, Jeddah, Saudi Arabia
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Venkat S. Gadepalli,

Affiliation Integrated Life Sciences Program, Virginia Commonwealth University, Richmond, Virginia, United States of America
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Shilpa Iyer,

Affiliations Center for the Study of Biological Complexity, Life Sciences Program, Virginia Commonwealth University, Richmond, Virginia, United States of America, Department of Chemical and Life Sciences Engineering, Virginia Commonwealth University, Richmond, Virginia, United States of America
⨯
Raj R. Rao

* E-mail: rrrao@vcu.edu

Affiliations Department of Human and Molecular Genetics, Virginia Commonwealth University, Richmond, United States of America, Integrated Life Sciences Program, Virginia Commonwealth University, Richmond, Virginia, United States of America, Center for the Study of Biological Complexity, Life Sciences Program, Virginia Commonwealth University, Richmond, Virginia, United States of America, Department of Chemical and Life Sciences Engineering, Virginia Commonwealth University, Richmond, Virginia, United States of America, Massey Cancer Center, Virginia Commonwealth University, Richmond, Virginia, United States of America
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Fibroblasts
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Cell cycle and cell division
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Gastric cancer
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Cell staining
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Synthesis phase
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DNA damage
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Apoptosis
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G1 phase
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