Mitochondrial Vulnerability and Increased Susceptibility to Nutrient-Induced Cytotoxicity in Fibroblasts from Leigh Syndrome French Canadian Patients

• Yan Burelle,

  Affiliation Faculty of Pharmacy, Université de Montréal, Montréal, Canada

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• Chantal Bemeur ,

  Contributed equally to this work with: Chantal Bemeur, Marie-Eve Rivard

  Current Address: Department of Nutrition, Université de Montréal, & Research Centre, Centre hospitalier de l’Université de Montréal—Tour Viger (R); Porte R12.458, 900, rue Saint-Denis, Montréal, Québec, Canada, H2X 0A9

  Affiliation Faculty of Pharmacy, Université de Montréal, Montréal, Canada

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• Marie-Eve Rivard ,

  Contributed equally to this work with: Chantal Bemeur, Marie-Eve Rivard

  Affiliations Montreal Heart Institute, Montreal, Canada, Department of Nutrition, Faculty of Medicine, Université de Montréal, Montreal, Canada

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• Julie Thompson Legault,

  Affiliations Montreal Heart Institute, Montreal, Canada, Department of Nutrition, Faculty of Medicine, Université de Montréal, Montreal, Canada

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• Gabrielle Boucher,

  Affiliation Montreal Heart Institute, Montreal, Canada

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• LSFC Consortium ,

  ¶The complete list of the LSFC Consortium members can be found in the Acknowledgments.

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• Charles Morin,

  Affiliation Department of Pediatrics and Clinical Research Unit, Complexe hospitalier de la Sagamie, Chicoutimi, QC, Canada

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• Lise Coderre ,

  ¶‡ These authors also contributed equally to this work.

  Affiliations Montreal Heart Institute, Montreal, Canada, Department of Nutrition, Faculty of Medicine, Université de Montréal, Montreal, Canada, Department of Medicine, Faculty of Medicine, Université de Montréal, Montréal, Canada

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• Christine Des Rosiers

  * E-mail: christine.des.rosiers@umontreal.ca

  ¶‡ These authors also contributed equally to this work.

  Affiliations Montreal Heart Institute, Montreal, Canada, Department of Nutrition, Faculty of Medicine, Université de Montréal, Montreal, Canada

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