Dexamethasone and Azathioprine Promote Cytoskeletal Changes and Affect Mesenchymal Stem Cell Migratory Behavior

Natália Schneider; Fabiany da Costa Gonçalves; Fernanda Otesbelgue Pinto; Patrícia Luciana da Costa Lopez; Anelise Bergmann Araújo; Bianca Pfaffenseller; Eduardo Pandolfi Passos; Elizabeth Obino Cirne-Lima; Luíse Meurer; Marcelo Lazzaron Lamers; Ana Helena Paz

doi:10.1371/journal.pone.0120538

Loading metrics

Open Access

Peer-reviewed

Research Article

Dexamethasone and Azathioprine Promote Cytoskeletal Changes and Affect Mesenchymal Stem Cell Migratory Behavior

Natália Schneider,

Affiliations Embryology and Cell Differentiation Laboratory, Experimental Research Center, Hospital de Clínicas de Porto Alegre, Ramiro Barcelos 2350, CEP 90035-903, Porto Alegre, RS, Brazil, Graduate Program in Gastroenterology and Hepatology Sciences, Universidade Federal do Rio Grande do Sul, Ramiro Barcelos 2400, CEP 90035-903, Porto Alegre, RS, Brazil
⨯
Fabiany da Costa Gonçalves,

Affiliations Embryology and Cell Differentiation Laboratory, Experimental Research Center, Hospital de Clínicas de Porto Alegre, Ramiro Barcelos 2350, CEP 90035-903, Porto Alegre, RS, Brazil, Graduate Program in Gastroenterology and Hepatology Sciences, Universidade Federal do Rio Grande do Sul, Ramiro Barcelos 2400, CEP 90035-903, Porto Alegre, RS, Brazil
⨯
Fernanda Otesbelgue Pinto,

Affiliation Embryology and Cell Differentiation Laboratory, Experimental Research Center, Hospital de Clínicas de Porto Alegre, Ramiro Barcelos 2350, CEP 90035-903, Porto Alegre, RS, Brazil
⨯
Patrícia Luciana da Costa Lopez,

Affiliation Experimental Research Center, Hospital de Clínicas de Porto Alegre, Ramiro Barcelos 2350, CEP 90035-903, Porto Alegre, RS, Brazil
⨯
Anelise Bergmann Araújo,

Affiliation Experimental Research Center, Hospital de Clínicas de Porto Alegre, Ramiro Barcelos 2350, CEP 90035-903, Porto Alegre, RS, Brazil
⨯
Bianca Pfaffenseller,

Affiliation Experimental Research Center, Hospital de Clínicas de Porto Alegre, Ramiro Barcelos 2350, CEP 90035-903, Porto Alegre, RS, Brazil
⨯
Eduardo Pandolfi Passos,

Affiliation Embryology and Cell Differentiation Laboratory, Experimental Research Center, Hospital de Clínicas de Porto Alegre, Ramiro Barcelos 2350, CEP 90035-903, Porto Alegre, RS, Brazil
⨯
Elizabeth Obino Cirne-Lima,

Affiliation Embryology and Cell Differentiation Laboratory, Experimental Research Center, Hospital de Clínicas de Porto Alegre, Ramiro Barcelos 2350, CEP 90035-903, Porto Alegre, RS, Brazil
⨯
Luíse Meurer,

Affiliation Graduate Program in Gastroenterology and Hepatology Sciences, Universidade Federal do Rio Grande do Sul, Ramiro Barcelos 2400, CEP 90035-903, Porto Alegre, RS, Brazil
⨯
Marcelo Lazzaron Lamers,

Affiliation Morphological Sciences Department, Health Basic Sciences Institute, Universidade Federal do Rio Grande do Sul, Rua Sarmento Leite 500, CEP 90050-170, Porto Alegre, RS, Brazil
⨯
Ana Helena Paz

* E-mail: anahpaz@gmail.com

Affiliations Embryology and Cell Differentiation Laboratory, Experimental Research Center, Hospital de Clínicas de Porto Alegre, Ramiro Barcelos 2350, CEP 90035-903, Porto Alegre, RS, Brazil, Graduate Program in Gastroenterology and Hepatology Sciences, Universidade Federal do Rio Grande do Sul, Ramiro Barcelos 2400, CEP 90035-903, Porto Alegre, RS, Brazil, Morphological Sciences Department, Health Basic Sciences Institute, Universidade Federal do Rio Grande do Sul, Rua Sarmento Leite 500, CEP 90050-170, Porto Alegre, RS, Brazil
⨯

Dexamethasone and Azathioprine Promote Cytoskeletal Changes and Affect Mesenchymal Stem Cell Migratory Behavior

Natália Schneider,
Fabiany da Costa Gonçalves,
Fernanda Otesbelgue Pinto,
Patrícia Luciana da Costa Lopez,
Anelise Bergmann Araújo,
Bianca Pfaffenseller,
Eduardo Pandolfi Passos,
Elizabeth Obino Cirne-Lima,
Luíse Meurer,
Marcelo Lazzaron Lamers

Published: March 10, 2015
https://doi.org/10.1371/journal.pone.0120538

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Mesenchymal stem cells
Is the Subject Area "Mesenchymal stem cells" applicable to this article?

Thanks for your feedback.
Actins
Is the Subject Area "Actins" applicable to this article?

Thanks for your feedback.
Cell polarity
Is the Subject Area "Cell polarity" applicable to this article?

Thanks for your feedback.
Cell migration
Is the Subject Area "Cell migration" applicable to this article?

Thanks for your feedback.
Drug therapy
Is the Subject Area "Drug therapy" applicable to this article?

Thanks for your feedback.
Immunosuppressives
Is the Subject Area "Immunosuppressives" applicable to this article?

Thanks for your feedback.
Inflammatory bowel disease
Is the Subject Area "Inflammatory bowel disease" applicable to this article?

Thanks for your feedback.
Morphometry
Is the Subject Area "Morphometry" applicable to this article?

Thanks for your feedback.