High Salt Intake Damages the Heart through Activation of Cardiac (Pro) Renin Receptors Even at an Early Stage of Hypertension

Yuka Hayakawa; Takuma Aoyama; Chiharu Yokoyama; Chihiro Okamoto; Hisaaki Komaki; Shingo Minatoguchi; Masamitsu Iwasa; Yoshihisa Yamada; Itta Kawamura; Masanori Kawasaki; Kazuhiko Nishigaki; Atsushi Mikami; Fumiaki Suzuki; Shinya Minatoguchi

doi:10.1371/journal.pone.0120453

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Open Access

Peer-reviewed

Research Article

High Salt Intake Damages the Heart through Activation of Cardiac (Pro) Renin Receptors Even at an Early Stage of Hypertension

Yuka Hayakawa,

Affiliation Department of Cardiology, Gifu University Graduate School of Medicine, Yanagido, Gifu, Japan
⨯
Takuma Aoyama,

Affiliation Department of Cardiology, Gifu University Graduate School of Medicine, Yanagido, Gifu, Japan
⨯
Chiharu Yokoyama,

Affiliation Department of Cardiology, Gifu University Graduate School of Medicine, Yanagido, Gifu, Japan
⨯
Chihiro Okamoto,

Affiliation Department of Cardiology, Gifu University Graduate School of Medicine, Yanagido, Gifu, Japan
⨯
Hisaaki Komaki,

Affiliation Department of Cardiology, Gifu University Graduate School of Medicine, Yanagido, Gifu, Japan
⨯
Shingo Minatoguchi,

Affiliation Department of Cardiology, Gifu University Graduate School of Medicine, Yanagido, Gifu, Japan
⨯
Masamitsu Iwasa,

Affiliation Department of Cardiology, Gifu University Graduate School of Medicine, Yanagido, Gifu, Japan
⨯
Yoshihisa Yamada,

Affiliation Department of Cardiology, Gifu University Graduate School of Medicine, Yanagido, Gifu, Japan
⨯
Itta Kawamura,

Affiliation Department of Cardiology, Gifu University Graduate School of Medicine, Yanagido, Gifu, Japan
⨯
Masanori Kawasaki,

Affiliation Department of Cardiology, Gifu University Graduate School of Medicine, Yanagido, Gifu, Japan
⨯
Kazuhiko Nishigaki,

Affiliation Department of Cardiology, Gifu University Graduate School of Medicine, Yanagido, Gifu, Japan
⨯
Atsushi Mikami,

Affiliation Department of Cardiology, Gifu University Graduate School of Medicine, Yanagido, Gifu, Japan
⨯
Fumiaki Suzuki,

Affiliation Department of Life Science, Gifu University, Yanagido, Gifu, Japan
⨯
Shinya Minatoguchi

* E-mail: minatos@gifu-u.ac.jp

Affiliation Department of Cardiology, Gifu University Graduate School of Medicine, Yanagido, Gifu, Japan
⨯

High Salt Intake Damages the Heart through Activation of Cardiac (Pro) Renin Receptors Even at an Early Stage of Hypertension

Yuka Hayakawa,
Takuma Aoyama,
Chiharu Yokoyama,
Chihiro Okamoto,
Hisaaki Komaki,
Shingo Minatoguchi,
Masamitsu Iwasa,
Yoshihisa Yamada,
Itta Kawamura,
Masanori Kawasaki

Published: March 23, 2015
https://doi.org/10.1371/journal.pone.0120453

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