Large Genomic Fragment Deletions and Insertions in Mouse Using CRISPR/Cas9

Luqing Zhang; Ruirui Jia; Norberto J. Palange; Achim Cchitvsanzwhoh Satheka; Jacques Togo; Yao An; Mabwi Humphrey; Luying Ban; Yan Ji; Honghong Jin; Xuechao Feng; Yaowu Zheng

doi:10.1371/journal.pone.0120396

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Open Access

Peer-reviewed

Research Article

Large Genomic Fragment Deletions and Insertions in Mouse Using CRISPR/Cas9

Luqing Zhang ,

Contributed equally to this work with: Luqing Zhang, Ruirui Jia, Norberto J. Palange

Affiliations Transgenic Research Center, School of Life Sciences, Northeast Normal University, Changchun, China, Key Laboratory of Molecular Epigenetics of Ministry of Education, Northeast Normal University, Changchun, China
⨯
Ruirui Jia ,

Contributed equally to this work with: Luqing Zhang, Ruirui Jia, Norberto J. Palange

Affiliation Transgenic Research Center, School of Life Sciences, Northeast Normal University, Changchun, China
⨯
Norberto J. Palange ,

Contributed equally to this work with: Luqing Zhang, Ruirui Jia, Norberto J. Palange

Affiliation Transgenic Research Center, School of Life Sciences, Northeast Normal University, Changchun, China
⨯
Achim Cchitvsanzwhoh Satheka,

Affiliation Transgenic Research Center, School of Life Sciences, Northeast Normal University, Changchun, China
⨯
Jacques Togo,

Affiliation Transgenic Research Center, School of Life Sciences, Northeast Normal University, Changchun, China
⨯
Yao An,

Affiliation Transgenic Research Center, School of Life Sciences, Northeast Normal University, Changchun, China
⨯
Mabwi Humphrey,

Affiliation Transgenic Research Center, School of Life Sciences, Northeast Normal University, Changchun, China
⨯
Luying Ban,

Affiliation Transgenic Research Center, School of Life Sciences, Northeast Normal University, Changchun, China
⨯
Yan Ji,

Affiliation Transgenic Research Center, School of Life Sciences, Northeast Normal University, Changchun, China
⨯
Honghong Jin,

Affiliation Transgenic Research Center, School of Life Sciences, Northeast Normal University, Changchun, China
⨯
Xuechao Feng ,

* E-mail: fengxc997@nenu.edu.cn (XCF); zhengyw442@nenu.edu.cn (YWZ)

Affiliation Key Laboratory of Molecular Epigenetics of Ministry of Education, Northeast Normal University, Changchun, China
⨯
Yaowu Zheng

* E-mail: fengxc997@nenu.edu.cn (XCF); zhengyw442@nenu.edu.cn (YWZ)

Affiliations Transgenic Research Center, School of Life Sciences, Northeast Normal University, Changchun, China, Key Laboratory of Molecular Epigenetics of Ministry of Education, Northeast Normal University, Changchun, China
⨯

Large Genomic Fragment Deletions and Insertions in Mouse Using CRISPR/Cas9

Luqing Zhang,
Ruirui Jia,
Norberto J. Palange,
Achim Cchitvsanzwhoh Satheka,
Jacques Togo,
Yao An,
Mabwi Humphrey,
Luying Ban,
Yan Ji,
Honghong Jin

Published: March 24, 2015
https://doi.org/10.1371/journal.pone.0120396

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