Deficiency for the Cysteine Protease Cathepsin L Impairs Myc-Induced Tumorigenesis in a Mouse Model of Pancreatic Neuroendocrine Cancer

• Nicola R. Brindle,

  Affiliation Swiss Institute for Experimental Cancer Research (ISREC), Swiss Federal Institute of Technology Lausanne (EPFL), Lausanne, Switzerland

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• Johanna A. Joyce,

  Affiliations Departments of Pathology and Department of Biochemistry and Biophysics, University of California San Francisco (UCSF), San Francisco, United States of America, Cancer Biology and Genetics Program, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

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• Fanya Rostker,

  Affiliation Departments of Pathology and Department of Biochemistry and Biophysics, University of California San Francisco (UCSF), San Francisco, United States of America

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• Elizabeth R. Lawlor,

  Current address: Department of Pediatrics, Translational Oncology Program, University of Michigan, Ann Arbor, Michigan, United States of America,

  Affiliation Departments of Pathology and Department of Biochemistry and Biophysics, University of California San Francisco (UCSF), San Francisco, United States of America

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• Lamorna Swigart-Brown,

  Affiliation Departments of Pathology and Department of Biochemistry and Biophysics, University of California San Francisco (UCSF), San Francisco, United States of America

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• Gerard Evan,

  Current address: Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom

  Affiliation Departments of Pathology and Department of Biochemistry and Biophysics, University of California San Francisco (UCSF), San Francisco, United States of America

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• Douglas Hanahan,

  Affiliation Swiss Institute for Experimental Cancer Research (ISREC), Swiss Federal Institute of Technology Lausanne (EPFL), Lausanne, Switzerland

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• Ksenya Shchors

  * E-mail: ksenya.shchors@epfl.ch

  Affiliations Swiss Institute for Experimental Cancer Research (ISREC), Swiss Federal Institute of Technology Lausanne (EPFL), Lausanne, Switzerland, Departments of Pathology and Department of Biochemistry and Biophysics, University of California San Francisco (UCSF), San Francisco, United States of America

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